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annotation rule: PRU01146

General rule information [?]

Accession PRU01146
Dates 6-JUL-2016 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51805; EPHD
Name Extended PHD (ePHD) domain
Function The extended plant homeodomain (ePHD) domain contains an N-terminal pre-PHD (C2HC zinc finger), a long linker, and a noncanonical PHD finger (C4HC3 zinc finger). The ePHD domain can bind dsDNA but not histones.

Propagated annotation [?]


Gene Ontology [?]

case (<Feature:PS51805:4=[CH]> and <Feature:PS51805:7=[CH]> and <Feature:PS51805:27=[CH]> and <Feature:PS51805:30=[CH]>) or (<Feature:PS51805:63=[CH]> and <Feature:PS51805:66=[CH]> and <Feature:PS51805:85=[CH]> and <Feature:PS51805:88=[CH]>) or (<Feature:PS51805:75=[CH]> and <Feature:PS51805:80=[CH]> and <Feature:PS51805:109=[CH]> and <Feature:PS51805:112=[CH]>)
GO:0008270; Molecular function: zinc ion binding.
GO:0046872; Molecular function: metal ion binding.

Keywords [?]

Metal-binding
Zinc
Zinc-finger
end case


Features [?]

case <Feature:PS51805:4=C> and <Feature:PS51805:7=C> and <Feature:PS51805:27=H> and <Feature:PS51805:30=C>
From: PS51805
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING     from     37       C2HC pre-PHD-type #        
else case <Feature:PS51805:4=[CH]> and <Feature:PS51805:7=[CH]> and <Feature:PS51805:27=[CH]> and <Feature:PS51805:30=[CH]>
ZN_FING     from     37       C2HC pre-PHD-type #; atypical        
else
ZN_FING     from     37       C2HC pre-PHD-type #; degenerate        
end case

case (<Feature:PS51805:63=[C]> and <Feature:PS51805:66=[C]> and <Feature:PS51805:85=[H]> and <Feature:PS51805:88=[C]>) and (<Feature:PS51805:75=[C]> and <Feature:PS51805:80=[C]> and <Feature:PS51805:109=[C]> and <Feature:PS51805:112=[H]>)
ZN_FING     61     to       PHD-type #        
else case (<Feature:PS51805:63=[CH]> and <Feature:PS51805:66=[CH]> and <Feature:PS51805:85=[CH]> and <Feature:PS51805:88=[CH]>) and (<Feature:PS51805:75=[CH]> and <Feature:PS51805:80=[CH]> and <Feature:PS51805:109=[CH]> and <Feature:PS51805:112=[CH]>)
ZN_FING     61     to       PHD-type #; atypical        
else
ZN_FING     61     to       PHD-type #; degenerate        
end case

case not <AnyFeature:PS50016~1,10~PS51805>
REGION     from     to       Extended PHD# domain (ePHD#)        
end case


Additional information [?]

Size range 95-155 amino acids
Related rules None
Repeats 1-2
Topology Undefined
Example P20659 (TRX_DROME)
Scope
Eukaryota
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]