ProRule PRU01146

Accession	PRU01146
Dates	6-JUL-2016 (Created) 22-NOV-2019 (Last updated, Version 3)
Data class	Domain;
Predictors	PROSITE; PS51805; EPHD
Name	Extended PHD (ePHD) domain
Function	The extended plant homeodomain (ePHD) domain contains an N-terminal pre-PHD (C2HC zinc finger), a long linker, and a noncanonical PHD finger (C4HC3 zinc finger). The ePHD domain can bind dsDNA but not histones.
Scope(s)	Eukaryota
Example(s)	P20659 (TRX_DROME);

From: PS51805
Key	From	To	Description	Tag	Condition	FTGroup
case <Feature:PS51805:4=C> and <Feature:PS51805:7=C> and <Feature:PS51805:27=H> and <Feature:PS51805:30=C>
ZN_FING	from	37	/note="C2HC pre-PHD-type #"
else case <Feature:PS51805:4=[CH]> and <Feature:PS51805:7=[CH]> and <Feature:PS51805:27=[CH]> and <Feature:PS51805:30=[CH]>
ZN_FING	from	37	/note="C2HC pre-PHD-type #; atypical"
else
ZN_FING	from	37	/note="C2HC pre-PHD-type #; degenerate"
end case
case (<Feature:PS51805:63=[C]> and <Feature:PS51805:66=[C]> and <Feature:PS51805:85=[H]> and <Feature:PS51805:88=[C]>) and (<Feature:PS51805:75=[C]> and <Feature:PS51805:80=[C]> and <Feature:PS51805:109=[C]> and <Feature:PS51805:112=[H]>)
ZN_FING	61	to	/note="PHD-type #"
else case (<Feature:PS51805:63=[CH]> and <Feature:PS51805:66=[CH]> and <Feature:PS51805:85=[CH]> and <Feature:PS51805:88=[CH]>) and (<Feature:PS51805:75=[CH]> and <Feature:PS51805:80=[CH]> and <Feature:PS51805:109=[CH]> and <Feature:PS51805:112=[CH]>)
ZN_FING	61	to	/note="PHD-type #; atypical"
else
ZN_FING	61	to	/note="PHD-type #; degenerate"
end case
case not <AnyFeature:PS50016~1,10~PS51805>
REGION	from	to	/note="Extended PHD# domain (ePHD#)"
end case