ProRule PRU01146
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PURL: https://purl.expasy.org/prosite/rule/PRU01146
General rule information
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| Accession | PRU01146 |
| Dates | 06-JUL-2016 (Created)
22-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51805; EPHD |
Name | Extended PHD (ePHD) domain |
| Function | The extended plant homeodomain (ePHD) domain contains an N-terminal pre-PHD (C2HC zinc finger), a long linker, and a noncanonical PHD finger (C4HC3 zinc finger). The ePHD domain can bind dsDNA but not histones. |
| Scope(s) |
Eukaryota |
| Example(s) | P20659; |
Propagated annotation
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Keywords
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| Metal-binding | |
| Zinc | |
| Zinc-finger | |
| end case | |
Gene Ontology
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| case (<Feature:PS51805:4=[CH]> and <Feature:PS51805:7=[CH]> and <Feature:PS51805:27=[CH]> and <Feature:PS51805:30=[CH]>) or (<Feature:PS51805:63=[CH]> and <Feature:PS51805:66=[CH]> and <Feature:PS51805:85=[CH]> and <Feature:PS51805:88=[CH]>) or (<Feature:PS51805:75=[CH]> and <Feature:PS51805:80=[CH]> and <Feature:PS51805:109=[CH]> and <Feature:PS51805:112=[CH]>) | |
| GO:0008270; Molecular function:zinc ion binding | |
| GO:0046872; Molecular function:metal ion binding | |
Features
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| From: PS51805 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <Feature:PS51805:4=C> and <Feature:PS51805:7=C> and <Feature:PS51805:27=H> and <Feature:PS51805:30=C> | ||||||||||||
| ZN_FING | from | 37 | /note="C2HC pre-PHD-type #" | |||||||||
| else case <Feature:PS51805:4=[CH]> and <Feature:PS51805:7=[CH]> and <Feature:PS51805:27=[CH]> and <Feature:PS51805:30=[CH]> | ||||||||||||
| ZN_FING | from | 37 | /note="C2HC pre-PHD-type #; atypical" | |||||||||
| else | ||||||||||||
| ZN_FING | from | 37 | /note="C2HC pre-PHD-type #; degenerate" | |||||||||
| end case | ||||||||||||
| case (<Feature:PS51805:63=[C]> and <Feature:PS51805:66=[C]> and <Feature:PS51805:85=[H]> and <Feature:PS51805:88=[C]>) and (<Feature:PS51805:75=[C]> and <Feature:PS51805:80=[C]> and <Feature:PS51805:109=[C]> and <Feature:PS51805:112=[H]>) | ||||||||||||
| ZN_FING | 61 | to | /note="PHD-type #" | |||||||||
| else case (<Feature:PS51805:63=[CH]> and <Feature:PS51805:66=[CH]> and <Feature:PS51805:85=[CH]> and <Feature:PS51805:88=[CH]>) and (<Feature:PS51805:75=[CH]> and <Feature:PS51805:80=[CH]> and <Feature:PS51805:109=[CH]> and <Feature:PS51805:112=[CH]>) | ||||||||||||
| ZN_FING | 61 | to | /note="PHD-type #; atypical" | |||||||||
| else | ||||||||||||
| ZN_FING | 61 | to | /note="PHD-type #; degenerate" | |||||||||
| end case | ||||||||||||
| case not <AnyFeature:PS50016~1,10~PS51805> | ||||||||||||
| REGION | from | to | /note="Extended PHD# domain (ePHD#)" | |||||||||
| end case | ||||||||||||
Additional information
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| Size range | 95-155 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [83] All [ 83 ]
- Retrieve set of proteins with 3D structure for this domain