ProRule PRU01163
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU01163 |
| Accession | PRU01163 |
| Dates | 1-NOV-2016 (Created)
19-NOV-2022 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51819; VOC |
Name | Vicinal oxygen chelate (VOC) domain |
| Function | The vicinal oxygen chelate (VOC) family of enzymes catalyzes a highly diverse set of chemistries that derives from one common mechanistic trait: bidentate coordination to a divalent metal center by a substrate or intermediate or transition state through vicinal oxygen atoms. |
| Scope(s) |
Bacteria Eukaryota Archaea Pyrococcus |
| Example(s) | Q8GPH6 (EHPR_ENTAG); |
Propagated annotation
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Keywords
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| case <FTGroup:1> | |
| Metal-binding | |
| end case | |
Features
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| From: PS51819 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="VOC #" | |||||||||
| ACT_SITE | 118 | 118 | /note="Proton donor/acceptor" | [EV] | ||||||||
| BINDING | 4 | 4 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
[HQ] | 1 | |||||||
| BINDING | 45 | 45 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
E | 1 | |||||||
| BINDING | 70 | 70 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
[HQ] | 1 | |||||||
| BINDING | 118 | 118 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
[EV] | 1 | |||||||
Additional information
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| Size range | 68-190 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [1] Bacteria [146] Eukaryota [64] All [ 211 ]
- Retrieve set of proteins with 3D structure for this domain