We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01173
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01173
General rule information
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| Accession | PRU01173 |
| Dates | 01-FEB-2017 (Created)
22-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51829; P_HOMO_B |
Name | P/Homo B domain |
| Function | The P/Homo B domain appears to be necessary to both fold and maintain the subtilisin-like active catalytic module and to regulate its specialized features of calcium and more acidic pH dependence. |
| Scope(s) |
Eukaryota Bacteria Viruses Ictalurivirus |
| Example(s) | P13134; |
Propagated annotation
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Features
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| From: PS51829 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="P/Homo B #" | |||||||||
Additional information
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| Size range | 89-176 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [10] Eukaryota [44] Viruses [1] All [ 55 ]
- Retrieve set of proteins with 3D structure for this domain