ProRule PRU01174
General rule information
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| Accession | PRU01174 |
| Dates | 2-MAR-2017 (Created)
22-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51830; FIIND |
Name | FIIND domain |
| Function | CARD8 and NLRP1 undergo autoproteolytic cleavage at a conserved SF/S motif within the "Function to Find Domain" (FIIND). |
| Scope(s) |
Eukaryota Euarchontoglires |
| Example(s) | Q9C000 (NLRP1_HUMAN); |
Propagated annotation
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Gene Ontology
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| case <Feature:PS51830:131-133=S-F-S> | |
| GO:0043280; Biological process:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | |
| end case | |
Features
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| From: PS51830 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="FIIND #" | |||||||||
| case <Feature:PS51830:131-133=S-F-S> | ||||||||||||
| SITE | 132 | 133 | /note="Cleavage; by autolysis" | |||||||||
| end case | ||||||||||||
Additional information
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| Size range | 108-296 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [15] All [ 15 ]
- Retrieve set of proteins with 3D structure for this domain