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annotation rule: PRU01174

General rule information [?]

Accession PRU01174
Dates 2-MAR-2017 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51830; FIIND
Name FIIND domain
Function CARD8 and NLRP1 undergo autoproteolytic cleavage at a conserved SF/S motif within the "Function to Find Domain" (FIIND).

Propagated annotation [?]

Gene Ontology [?]

case <Feature:PS51830:131-133=S-F-S>
GO:0043280; Biological process: positive regulation of cysteine-type endopeptidase activity involved in apoptotic process.
end case

Features [?]

From: PS51830
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       FIIND #        
case <Feature:PS51830:131-133=S-F-S>
SITE     132     133       Cleavage; by autolysis        
end case

Additional information [?]

Size range 108-296 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9C000 (NLRP1_HUMAN)
Eukaryota; Euarchontoglires
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [15]