ProRule PRU01174

General rule information [?]

Accession PRU01174
Dates 2-MAR-2017 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51830; FIIND
Name FIIND domain
Function CARD8 and NLRP1 undergo autoproteolytic cleavage at a conserved SF/S motif within the "Function to Find Domain" (FIIND).
Scope(s) Eukaryota
Example(s) Q9C000 (NLRP1_HUMAN);

Propagated annotation [?]

Gene Ontology [?]

case <Feature:PS51830:131-133=S-F-S>
GO:0043280; Biological process:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
end case

Features [?]

From: PS51830
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="FIIND #"
case <Feature:PS51830:131-133=S-F-S>
SITE 132 133 /note="Cleavage; by autolysis"
end case

Additional information [?]

Size range 108-296 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]