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annotation rule: PRU01189

General rule information [?]

Accession PRU01189
Dates 23-OCT-2017 (Created)
23-OCT-2017 (Last updated, Version 1)
Data class Domain
Predictors PROSITE; PS51843; NR_LBD
Names Nuclear receptor (NR) ligand-binding (LBD) domain; HOLI domain
Function he NR LBD plays a crucial role in ligand-mediated NR activity. In addition to its role is ligand regognition, the LBD also contains a ligand- dependent AF-2.

Propagated annotation [?]

Keywords [?]

Features [?]

From: PS51843
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       NR LBD #        
REGION     226     to       AF-2        

Additional information [?]

Size range 200-400 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P49843 (GCR_ONCMY)
Eukaryota; Metazoa
Viruses; Alpharetrovirus
Comments None


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.

UniProtKB rule member sequences [?]