ProRule PRU01189

General rule information [?]

Accession PRU01189
Dates 23-OCT-2017 (Created)
7-DEC-2023 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51843; NR_LBD
Name Nuclear receptor (NR) ligand-binding (LBD) domain
Function The NR LBD plays a crucial role in ligand-mediated NR activity. In addition to its role in ligand recognition, the LBD also contains a ligand- dependent AF-2 region.
Scope(s) Eukaryota
Example(s) P49843 (GCR_ONCMY);

Propagated annotation [?]

Keywords [?]

Features [?]

From: PS51843
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="NR LBD #"
REGION 226 to /note="AF-2"

Additional information [?]

Size range 200-400 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]