$VAR1 = '/images/prosite/prosite_trans.png'; ProRule PRU01189

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General rule information [?]

Accession PRU01189
Dates 23-OCT-2017 (Created)
22-NOV-2019 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51843; NR_LBD
Names Nuclear receptor (NR) ligand-binding (LBD) domain; HOLI domain
Function he NR LBD plays a crucial role in ligand-mediated NR activity. In addition to its role is ligand regognition, the LBD also contains a ligand- dependent AF-2.

Propagated annotation [?]

Keywords [?]

Features [?]

From: PS51843
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       NR LBD #        
REGION     226     to       AF-2        

Additional information [?]

Size range 200-400 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P49843 (GCR_ONCMY)
Eukaryota; Metazoa
Viruses; Alpharetrovirus
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]