ProRule PRU01189
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU01189 |
| Accession | PRU01189 |
| Dates | 23-OCT-2017 (Created)
7-DEC-2023 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51843; NR_LBD |
Name | Nuclear receptor (NR) ligand-binding (LBD) domain |
| Function | The NR LBD plays a crucial role in ligand-mediated NR activity. In addition to its role in ligand recognition, the LBD also contains a ligand- dependent AF-2 region. |
| Scope(s) |
Eukaryota Metazoa Viruses Alpharetrovirus |
| Example(s) | P49843 (GCR_ONCMY); |
Propagated annotation
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Keywords
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Features
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| From: PS51843 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="NR LBD #" | |||||||||
| REGION | 226 | to | /note="AF-2" | |||||||||
Additional information
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| Size range | 200-400 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [486] Viruses [1] All [ 487 ]
- Retrieve set of proteins with 3D structure for this domain