ProRule PRU01194
General rule information
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| Accession | PRU01194 |
| Dates | 16-NOV-2017 (Created)
22-NOV-2019 (Last updated, Version 2) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51847; SMP |
Name | Synaptotagmin-like mitochondrial lipid-binding proteins (SMP) domain |
| Function | The SMP domain is able to homo- or heterodimerize, harbors lipids in a hydrophobic cavity and mediates lipid transfer between two adjacent bilayers independently of membrane fusion and fission reactions. |
| Scope(s) |
Eukaryota |
| Example(s) | C5DLL1 (MDM34_LACTC); |
Propagated annotation
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Comments
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| DOMAIN | The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers. |
Keywords
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Features
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| From: PS51847 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="SMP-LTD #" | |||||||||
Additional information
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| Size range | 150-700 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [202] All [ 202 ]
- Retrieve set of proteins with 3D structure for this domain