ProRule PRU01194

General rule information [?]

Accession PRU01194
Dates 16-NOV-2017 (Created)
22-NOV-2019 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS51847; SMP
Name Synaptotagmin-like mitochondrial lipid-binding proteins (SMP) domain
Function The SMP domain is able to homo- or heterodimerize, harbors lipids in a hydrophobic cavity and mediates lipid transfer between two adjacent bilayers independently of membrane fusion and fission reactions.
Scope(s) Eukaryota
Example(s) C5DLL1 (MDM34_LACTC);

Propagated annotation [?]

Comments [?]

DOMAINThe SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

Keywords [?]

Features [?]

From: PS51847
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="SMP-LTD #"

Additional information [?]

Size range 150-700 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]