ProRule PRU01205

General rule information [?]

Accession PRU01205
Dates 20-FEB-2018 (Created)
5-JAN-2023 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51858; PPPDE
Name PPPDE domain
Function The PPPDE domain has a papain-like fold, in which a catalytic dyad is formed by a conserved N-terminal histidine residue on a beta-strand (beta2) and a conserved C-terminal cysteine residue on a following alpha- helix (alpha3).
Scope(s) Eukaryota
Example(s) Q9D291 (DESI2_MOUSE);

Propagated annotation [?]

Keywords [?]

end case

Gene Ontology [?]

case <FTGroup:1>
GO:0008233; Molecular function:peptidase activity

Features [?]

From: PS51858
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="PPPDE #"
ACT_SITE 32 32 H 1
ACT_SITE 107 107 C 1

Additional information [?]

Size range 130-230 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]