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annotation rule: PRU01205

General rule information [?]

Accession PRU01205
Dates 20-FEB-2018 (Created)
5-JAN-2023 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51858; PPPDE
Name PPPDE domain
Function The PPPDE domain has a papain-like fold, in which a catalytic dyad is formed by a conserved N-terminal histidine residue on a beta-strand (beta2) and a conserved C-terminal cysteine residue on a following alpha- helix (alpha3).

Propagated annotation [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0008233; Molecular function: peptidase activity.

Keywords [?]

end case

Features [?]

From: PS51858
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PPPDE #        
ACT_SITE     32     32             H   1
ACT_SITE     107     107             C   1

Additional information [?]

Size range 130-230 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9D291 (DESI2_MOUSE)
Viruses; Reovirales
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]