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annotation rule: PRU01216

General rule information [?]

Accession PRU01216
Dates 25-JUL-2018 (Created)
22-NOV-2019 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS51868; PEPTIDASE_S39
Name Peptidase family S39 domain
Function A triad composed of a histidine, an aspartate and a serine residue constitute the active centre of the peptidase S39 family domain.

Propagated annotation [?]

Description [?]

case <FTGroup:1>
Contains: RecName: Full=Serine protease; EC 3.4.21.-;

Gene Ontology [?]

GO:0004252; Molecular function: serine-type endopeptidase activity.

Keywords [?]

end case

Features [?]

From: PS51868
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase S39 #        
ACT_SITE     49     49       For protease activity     H   1
ACT_SITE     83     83       For protease activity     D   1
ACT_SITE     153     153       For protease activity     S   1

Additional information [?]

Size range 180-200 amino acids
Related rules None
Repeats 1
Topology Undefined
Example O73564 (P2A_SBMVA)
Viruses; Riboviria
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Viruses [17]