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PRU01230


General rule information [?]

Accession PRU01230
Dates 7-JAN-2019 (Created)
19-NOV-2022 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS51882; G_ALPHA
Name G-alpha domain
Function The G-alpha domain contains a binding site for guanine nucleotide and possesses GTPase activity.

Propagated annotation [?]


Gene Ontology [?]

GO:0031683; Molecular function: G-protein beta/gamma-subunit complex binding.
GO:0003924; Molecular function: GTPase activity.
GO:0005525; Molecular function: GTP binding.
case <FTGroup:1>
GO:0046872; Molecular function: metal ion binding.
end case

GO:0005834; Cellular component: heterotrimeric G-protein complex.

Keywords [?]

GTP-binding
Nucleotide-binding
Transducer
case <FTGroup:1>
Metal-binding
end case


Features [?]

From: PS51882
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       G-alpha #        
REGION     4     17       G1 motif        
REGION     146     154       G2 motif        
REGION     169     178       G3 motif        
REGION     238     245       G4 motif        
REGION     298     303       G5 motif        
BINDING     16     16       /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240     S   1
BINDING     154     154       /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240     T   1

Additional information [?]

Size range 310-490 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P87032 (GPA1_USTMA)
Scope
Eukaryota
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]