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annotation rule: PRU01247

General rule information [?]

Accession PRU01247
Dates 3-JUL-2019 (Created)
22-NOV-2019 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51899; TYR_RECOMBINASE_FLP
Name Flp-type tyrosine recombinase domain
Function The yeast Flp recombinase is a tyrosine site-specific recombinase responsible for the control of plasmid copy number. All members of the tyrosine, or lambda integrase family of site-specific recombinases proceed via a 3' covalent phosphotyrosine intermediate to catalyze a variety of DNA rearrangements, including insertions, deletions, and inversions, depending on the location and orientation of cognate recombination target sites.

Propagated annotation [?]


Comments [?]

Similarity Belongs to the 'phage' integrase family.

Gene Ontology [?]

case <FT:2>
GO:0015074; Biological process: DNA integration.
GO:0006310; Biological process: DNA recombination.

Keywords [?]

end case


Features [?]

From: PS51899
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Tyr recombinase Flp-type #        
ACT_SITE     207     207       O-(3'-phospho-DNA)-tyrosine intermediate     Y  

Additional information [?]

Size range 280-290 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P13769 (FLP_ZYGBA)
Scope
Eukaryota; Saccharomycetaceae
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]