We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01277
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01277
General rule information
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| Accession | PRU01277 |
| Dates | 24-JUN-2020 (Created)
24-JUN-2020 (Last updated, Version 2) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51929; COV_N_CTD |
Name | Coronavirus nucleocapsid (CoV N) protein C-terminal domain |
| Function | CoV N proteins contain two structured domains: the N-terminal domain (NTD; also called RBD), which is responsible for RNA binding, and the C- terminal domain (CTD; also called DD), which mediates oligomerization and RNA binding. |
| Scope(s) |
Viruses Riboviria |
| Example(s) | Q64960; |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0019013; Cellular component:viral nucleocapsid |
| GO:0003723; Molecular function:RNA binding |
Features
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| From: PS51929 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="CoV N CTD #" | |||||||||
Additional information
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| Size range | 110-130 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [64] All [ 64 ]
- Retrieve set of proteins with 3D structure for this domain