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annotation rule: PRU01283 |
Accession | PRU01283 |
Dates | 6-AUG-2020 (Created) 6-AUG-2020 (Last updated, Version 1) |
Data class | Domain |
Predictors | PROSITE; PS51934; LRAT |
Name | LRAT domain |
Function | The NlpC/P60 LRAT-type family includes lecithin-retinol acyltransferase (LRAT), nematode developmental regulator Egl-26, class II tumor suppressor H-rev107 and proteins from poxviruses and animal positive- strand RNA viruses, which share a common catalytic domain fold and an unconventional active site. Several members of the NlpC/P60 LRAT-type family are able to act as transferases/esterases utilizing glycerophospholipids as acyl donors. |
From: PS51934 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | LRAT # | |||||||||
ACT_SITE | 11 | 11 | H | 1 | ||||||||
ACT_SITE | 23 | 23 | H | 1 | ||||||||
ACT_SITE | 102 | 102 | Acyl-thioester intermediate | C | 1 |
Size range | 85-155 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | Q9JI61 (LRAT_RAT) |
Scope | Eukaryota; Euarchontoglires |
Comments | None |
Eukaryota | [21] | |
Viruses | [7] | |
All | [ 28 ] |