ProRule PRU01283

General rule information [?]

Accession PRU01283
Dates 6-AUG-2020 (Created)
-- (Last updated, Version 1)
Data class Domain;
Predictors PROSITE; PS51934; LRAT
Name LRAT domain
Function The NlpC/P60 LRAT-type family includes lecithin-retinol acyltransferase (LRAT), nematode developmental regulator Egl-26, class II tumor suppressor H-rev107 and proteins from poxviruses and animal positive- strand RNA viruses, which share a common catalytic domain fold and an unconventional active site. Several members of the NlpC/P60 LRAT-type family are able to act as transferases/esterases utilizing glycerophospholipids as acyl donors.
Scope(s) Eukaryota
Example(s) Q9JI61 (LRAT_RAT);

Propagated annotation [?]

Features [?]

From: PS51934
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="LRAT #"
ACT_SITE 11 11 H 1
ACT_SITE 23 23 H 1
ACT_SITE 102 102 /note="Acyl-thioester intermediate" C 1

Additional information [?]

Size range 85-155 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]