We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01288
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01288
General rule information
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| Accession | PRU01288 |
| Dates | 17-SEP-2020 (Created)
17-SEP-2020 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51939; XRRM |
Name | xRRM domain |
| Function | The xRRM interacts with both single- and double-stranded RNA using the beta-sheet surface and the C-terminal tail, which forms a helical extension of alpha3 (alpha3x) that binds to the RNA major groove. |
| Scope(s) |
Eukaryota |
| Example(s) | Q05CL8; |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:1990904; Cellular component:ribonucleoprotein complex |
Features
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| From: PS51939 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="xRRM #" | |||||||||
Additional information
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| Size range | 110-170 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [19] All [ 19 ]
- Retrieve set of proteins with 3D structure for this domain