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annotation rule: PRU01304

General rule information [?]

Accession PRU01304
Dates 29-JAN-2021 (Created)
29-JAN-2021 (Last updated, Version 1)
Data class Domain
Predictors PROSITE; PS51959; ENDOU
Name Eukaryotic uridylate-specific endoribonuclease (EndoU) domain
Function The EndoU domain cleaves RNA at uridylates and release 2',3'-cyclic phosphodiester ends.

Propagated annotation [?]

Description [?]

+ RecName: EC 3.1.-.-;

Comments [?]

Function Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini.
Cofactor Mn(2+)
Subunit Monomer.
Similarity Belongs to the ENDOU family.

Gene Ontology [?]

case <FTGroup:1>
GO:0003723; Molecular function: RNA binding.
GO:0004521; Molecular function: endoribonuclease activity.
GO:0046872; Molecular function: metal ion binding.

Keywords [?]

end case

Features [?]

From: PS51959
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       EndoU #        
ACT_SITE     149     149             H   1
ACT_SITE     164     164             H   1
ACT_SITE     207     207             K   1

Additional information [?]

Size range 260-280 amino acids
Related rules None
Repeats 1
Topology Undefined
Example A8E627 (ENDUD_XENLA)
Eukaryota; Metazoa
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]