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annotation rule: PRU01322

General rule information [?]

Accession PRU01322
Dates 16-JUN-2021 (Created)
16-JUN-2021 (Last updated, Version 1)
Data class Domain
Predictors PROSITE; PS51978; PBC
Name PBC domain
Function The PBC class of TALE homeodomain proteins includes the products of the vertebrate Pbx1, Pbx2, Pbx3 and Pbx4, Caenorhabditis elegans ceh-20, ceh-40 and ceh-60 and the Drosophila extradenticle (exd) genes. The sequence similarity between the PBC proteins extends downstream of the homeodomain for about 15 amino acids, and upstream of the homeodomain is a 180-amino acid dimerization domain termed PBC. The PBC domain can be further subdivided into an A and B region.

Propagated annotation [?]


Comments [?]

Subcellular location Nucleus.
Similarity Belongs to the TALE/PBX homeobox family.

Keywords [?]


Features [?]

From: PS51978
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PBC #        
REGION     8     89       PBC-A #        
REGION     92     188       PBC-B #        

Additional information [?]

Size range 175-205 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q6IR52 (PBX2_XENLA)
Scope
Eukaryota; Metazoa
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [18]