PRU01322
General rule information
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| Accession | PRU01322 |
| Dates | 16-JUN-2021 (Created) 16-JUN-2021 (Last updated, Version 1) |
| Data class | Domain |
| Predictors | PROSITE; PS51978; PBC |
| Name | PBC domain |
| Function | The PBC class of TALE homeodomain proteins includes the products of the vertebrate Pbx1, Pbx2, Pbx3 and Pbx4, Caenorhabditis elegans ceh-20, ceh-40 and ceh-60 and the Drosophila extradenticle (exd) genes. The sequence similarity between the PBC proteins extends downstream of the homeodomain for about 15 amino acids, and upstream of the homeodomain is a 180-amino acid dimerization domain termed PBC. The PBC domain can be further subdivided into an A and B region. |
Propagated annotation
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Comments
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| Subcellular location | Nucleus. |
| Similarity | Belongs to the TALE/PBX homeobox family. |
Keywords
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Features
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| From: PS51978 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | PBC # | |||||||||
| REGION | 8 | 89 | PBC-A # | |||||||||
| REGION | 92 | 188 | PBC-B # | |||||||||
Additional information
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| Size range | 175-205 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q6IR52 (PBX2_XENLA) |
| Scope | Eukaryota; Metazoa |
| Comments | None |
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UniProtKB rule member sequences
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