We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01324
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01324
General rule information
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| Accession | PRU01324 |
| Dates | 21-JUL-2021 (Created)
21-JUL-2021 (Last updated, Version 2) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51980; OCEL |
Name | Occludin/ELL (OCEL) domain |
| Function | The ~110-amino acid occludin/ELL (OCEL) domain is necessary for interactions between occludin and ZO-1, actin, and multiple kinases and may also mediate homotypic occludin-occludin interactions. The C-terminal OCEL domain of ELL is also important for its function due to its interaction with other proteins. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | Q3UZP0; |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the ELL/occludin family. |
Features
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| From: PS51980 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="OCEL #" | |||||||||
Additional information
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| Size range | 105-115 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [22] All [ 22 ]
- Retrieve set of proteins with 3D structure for this domain