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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01328


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01328
General rule information [?]

Accession PRU01328
Dates 20-SEP-2021 (Created)
20-SEP-2021 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS51984; CPB1
Name Cryptic Polo-Box 1 (CPB1) domain
Function Plk4s target mother centrioles through an interaction between their CPB and acidic regions in the centriolar receptors SPD-2/Cep192 and/or Asterless/Cep152.
Scope(s) Eukaryota
Metazoa
Example(s) B4LDJ6;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

Keywords [?]

Cytoplasm
Cytoskeleton

Gene Ontology [?]

GO:0007099; Biological process:centriole replication
GO:0005814; Cellular component:centriole
GO:0005737; Cellular component:cytoplasm

Features [?]

From: PS51984
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Cryptic POLO box 1 (CPB1) #"

Additional information [?]

Size range 110-125 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]