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| annotation rule: PRU01329 |
General rule information
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| Accession | PRU01329 |
| Dates | 20-SEP-2021 (Created) 20-SEP-2021 (Last updated, Version 1) |
| Data class | Domain |
| Predictors | PROSITE; PS51985; CPB2 |
| Name | Cryptic Polo-Box 2 (CPB2) domain |
| Function | Plk4s target mother centrioles through an interaction between their CPB and acidic regions in the centriolar receptors SPD-2/Cep192 and/or Asterless/Cep152. |
Propagated annotation
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Comments
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| Similarity | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. |
Gene Ontology
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GO:0005737; Cellular component: cytoplasm.
GO:0007099; Biological process: centriole replication.
GO:0005814; Cellular component: centriole.
GO:0007099; Biological process: centriole replication.
GO:0005814; Cellular component: centriole.
Keywords
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Features
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| From: PS51985 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | Cryptic POLO box 2 (CPB2) # | |||||||||
Additional information
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| Size range | 100-120 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q2LYK3 (PLK4_DROPS) |
| Scope | Eukaryota; Metazoa |
| Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [23]
- Retrieve set of proteins with 3D structure for this domain