General rule information
[?]
Accession |
PRU01332 |
Dates |
8-OCT-2021 (Created) 14-MAY-2022 (Last updated, Version 2) |
Predictors |
PROSITE; PS51988; HERPESVIRUS_UL32
|
Name |
Herpesviridae UL32 packaging protein family |
Function |
The Herpesviridae UL32 family proteins form homopentameric rings with a positively charged central channel that binds double-stranded DNA. |
Propagated annotation
[?]
Function |
Plays a role in efficient localization of neo-synthesized capsids to nuclear replication compartments, thereby controlling cleavage and packaging of virus genomic DNA. |
Similarity |
Belongs to the herpesviridae UL32 protein family. |
GO:0042025; Cellular component: host cell nucleus.
GO:0030430; Cellular component: host cell cytoplasm.
GO:0019031; Cellular component: viral envelope.
case (<Feature:PS51988:67=CH> and <Feature:PS51988:70=CH> and <Feature:PS51988:145=HC> and <Feature:PS51988:151=CH>) or (<Feature:PS51988:220=CH> and <Feature:PS51988:221=CH> and <Feature:PS51988:445=HC> and <Feature:PS51988:483=CH>) or (<Feature:PS51988:328=CH> and <Feature:PS51988:331=CH> and <Feature:PS51988:398=HC> and <Feature:PS51988:405=CH>)
end case
case <FTGroup:1>
From: PS51988 |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
REGION
|
|
67
|
|
151
|
|
Zinc finger #1
|
|
|
|
|
|
|
end case
case <FTGroup:3>
REGION
|
|
220
|
|
483
|
|
Zinc finger #3
|
|
|
|
|
|
|
end case
case <FTGroup:2>
REGION
|
|
328
|
|
405
|
|
Zinc finger #2
|
|
|
|
|
|
|
end case
BINDING
|
|
67
|
|
67
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#1
|
|
|
|
[CH]
|
|
1
|
BINDING
|
|
70
|
|
70
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#1
|
|
|
|
[CH]
|
|
1
|
BINDING
|
|
145
|
|
145
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#1
|
|
|
|
[CH]
|
|
1
|
BINDING
|
|
151
|
|
151
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#1
|
|
|
|
[CH]
|
|
1
|
BINDING
|
|
220
|
|
220
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#3
|
|
|
|
[CH]
|
|
3
|
BINDING
|
|
221
|
|
221
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#3
|
|
|
|
[CH]
|
|
3
|
BINDING
|
|
328
|
|
328
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#2
|
|
|
|
[CH]
|
|
2
|
BINDING
|
|
331
|
|
331
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#2
|
|
|
|
[CH]
|
|
2
|
BINDING
|
|
398
|
|
398
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#2
|
|
|
|
[CH]
|
|
2
|
BINDING
|
|
405
|
|
405
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#2
|
|
|
|
[CH]
|
|
2
|
BINDING
|
|
445
|
|
445
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#3
|
|
|
|
[CH]
|
|
3
|
BINDING
|
|
483
|
|
483
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#3
|
|
|
|
[CH]
|
|
3
|
Additional information
[?]
Size range |
430-620 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
Q66671 (UL32_EHV2) |
Scope |
Viruses; Herpesviridae |
Comments |
None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]