We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01352
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01352
General rule information
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| Accession | PRU01352 |
| Dates | 11-OCT-2022 (Created)
11-OCT-2022 (Last updated, Version 2) |
| Data class | Domain; |
| Predictors |
PROSITE; PS52008; GH81 |
Name | Glycosyl hydrolases family 81 (GH81) domain |
| Function | The GH family 81 (GH81) includes proteins with endo-beta-1,3- glucanase widely distributed in plants, fungi, bacteria, archaea and viruses. |
| Scope(s) |
Eukaryota Bacteria |
| Example(s) | Q9KG76; |
Propagated annotation
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Identifier, protein and gene names
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| case <FTGroup:1> | |
| Protein name | + RecName: EC=2.1.1.-; |
| end case | |
Comments
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| SIMILARITY | Belongs to the glycosyl hydrolase 81 family. |
Keywords
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Gene Ontology
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| case <FTGroup:1> | |
| GO:0042973; Molecular function:glucan endo-1,3-beta-D-glucosidase activity | |
Features
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| From: PS52008 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="GH81 #" | |||||||||
| REGION | from | 224 | /note="beta-sandwich subdomain #" | |||||||||
| REGION | 225 | 322 | /note="alpha/beta subdomain #" | |||||||||
| REGION | 337 | to | /note="(alpha/beta)6 barrel subdomain #" | |||||||||
| ACT_SITE | 443 | 443 | D | 1 | ||||||||
| ACT_SITE | 518 | 518 | E | 1 | ||||||||
| ACT_SITE | 522 | 522 | E | 1 | ||||||||
Additional information
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| Size range | 647-729 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [3] Eukaryota [8] All [ 11 ]
- Retrieve set of proteins with 3D structure for this domain