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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01354


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01354
General rule information [?]

Accession PRU01354
Dates 24-OCT-2022 (Created)
24-OCT-2022 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS52010; COLLECTRIN_LIKE
Name Collectrin-like domain
Function The collectrin-like domain mediates homodimerization. It consists of a small extracellular neck subdomain, which adopts a ferredoxin-like fold, a long linker, and a single transmembrane (TM) helix.
Scope(s) Eukaryota
Eutheria
Example(s) Q9HBJ8;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONCell membrane; Single-pass type I membrane protein.

Keywords [?]

Cell membrane
Membrane
Transmembrane
Transmembrane helix

Gene Ontology [?]

GO:0005886; Cellular component:plasma membrane

Features [?]

From: PS52010
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Collectrin-like #"
TRANSMEM 122 142 /note="Helical"

Additional information [?]

Size range 192-202 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]