ProRule PRU01360
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU01360 |
| Accession | PRU01360 |
| Dates | 31-JAN-2023 (Created)
3-FEB-2023 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS52016; TONB_DEPENDENT_REC_3 |
Name | TonB-dependent receptor proteins |
| Function | TonB-dependent receptors (TBDRs) are transport proteins found at the outer membrane (OM) to allow Gram-negative bacteria to uptake scarce resources from competitive environments with very high affinity. All of them share the same basic architecture, a C-terminal membrane-embedded 22-strand antiparallel beta-barrel domain that is sealed by a conserved N-terminal globular 'plug' domain (also called 'cork' or 'hatch'). |
| Scope(s) |
Bacteria |
| Example(s) | Q9KVI9 (BTUB_VIBCH); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Cell outer membrane; Multi-pass membrane protein. |
| SIMILARITY | Belongs to the TonB-dependent receptor family. |
Keywords
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Gene Ontology
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| GO:0009279; Cellular component:cell outer membrane |
Cross-references
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Features
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| From: PS52016 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | 119 | /note="TBDR plug #" | |||||||||
| DOMAIN | 124 | to | /note="TBDR beta-barrel #" | |||||||||
Additional information
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| Size range | 80-1001 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [126] All [ 126 ]
- Retrieve set of proteins with 3D structure for this domain