We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01376
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01376
General rule information
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| Accession | PRU01376 |
| Dates | 25-JUL-2023 (Created)
27-JUL-2023 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS52032; MARR_BRCT_CHROMO |
Name | MarR-like, BRCT and chromo domains module |
| Function | The N-terminus of the BAF155/SMARCC1 and BAF170/SMARCC2 subunits contain a putative DNA-binding MarR-like domain, a chromo domain and a BRCT domain that are interconnected to each other to form a distinct module. This N-terminal module could participate in an interaction involving both protein and nucleic acid components. |
| Scope(s) |
Eukaryota Euarchontoglires |
| Example(s) | P97496; |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the SMARCC family. |
Keywords
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Gene Ontology
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| GO:0000785; Cellular component:chromatin |
| GO:0006338; Biological process:chromatin remodeling |
| GO:0016514; Cellular component:SWI/SNF complex |
Features
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| From: PS52032 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REGION | from | to | /note="MarR-like, BRCT and chromo domains module #" | |||||||||
| DOMAIN | 11 | 137 | /note="MarR-like #" | |||||||||
| DOMAIN | 141 | 184 | /note="BRCT #1; N-terminus" | |||||||||
| DOMAIN | 190 | 218 | /note="Chromo #" | |||||||||
| DOMAIN | 234 | 258 | /note="BRCT #1; C-terminus" | |||||||||
Additional information
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| Size range | 274-275 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [4] All [ 4 ]
- Retrieve set of proteins with 3D structure for this domain