ProRule PRU01397
General rule information
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| Accession | PRU01397 |
| Dates | 27-SEP-2024 (Created)
-- (Last updated, Version 1) |
| Data class | Domain; |
| Predictors |
PROSITE; PS52052; PEHE |
Name | PEHE domain |
| Function | The PEHE domain, named after four highly conserved characteristic amino acidic residues (P, E, H, E) is found in subunits of two protein complexes, MSL and NSL, involved in histone acetylation in both vertebrates and invertebrates. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | Q0IHW6 (KAL1L_XENTR); |
Propagated annotation
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Comments
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| SUBUNIT | Interacts (via PEHE domain) with KAT8 (via HAT domain); the interaction is direct. |
Features
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| From: PS52052 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="PEHE #" | |||||||||
| REGION | 25 | 43 | /note="Interaction with KAT8 HAT domain" | |||||||||
Additional information
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| Size range | 115-152 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [9] All [ 9 ]
- Retrieve set of proteins with 3D structure for this domain