PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01402


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01402
General rule information [?]

Accession PRU01402
Dates 13-FEB-2025 (Created)
13-FEB-2025 (Last updated, Version 2)
Data class Domain;
Predictors PROSITE; PS52057; GLD
Name GTP-binding protein-like domain (GLD)
Function It has been assumed that GLDs are functionally GTPases but the efficient hydrolysis of GTP, ATP, UTP and CTP shows that GLDs should be classified not as GTPases but as NTPases.
Scope(s) Eukaryota
Metazoa
Example(s) Q99490;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the centaurin gamma-like family.

Keywords [?]

GTP-binding
Nucleotide-binding

Gene Ontology [?]

GO:0003924; Molecular function:GTPase activity
GO:0005525; Molecular function:GTP binding

Features [?]

From: PS52057
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="GLD #"

Additional information [?]

Size range 175-185 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]