ProRule PRU01454
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PURL: https://purl.expasy.org/prosite/rule/PRU01454
General rule information
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| Accession | PRU01454 |
| Dates | 17-JUN-2026 (Created)
17-JUN-2026 (Last updated, Version ) |
| Data class | Domain; |
| Predictors |
PROSITE; PS52110; FV_VP35_CC_OD |
Name | Filovirus viral protein 35 (VP35) coiled-coil oligomerization domain (OD) |
| Function | Homo-oligomerization of VP35 through ODs is essential for its function in viral replication and transcription as well as maximizing the interferon-antagonist activity. |
| Scope(s) |
Viruses Filoviridae |
| Example(s) | P35259 (VP35_MABVM); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + AltName: Full=Polymerase cofactor VP35; |
Comments
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| SUBCELLULAR LOCATION | Virion. Host cytoplasm. |
| SIMILARITY | Belongs to the filoviridae polymerase cofactor VP35 family. |
Keywords
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Gene Ontology
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| GO:0030430; Cellular component:host cell cytoplasm |
Features
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| From: PS52110 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="VP35 coiled-coil oligomerization #" | |||||||||
Additional information
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| Size range | 75-81 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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