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annotation rule: PRU10001

General rule information [?]

Accession PRU10001
Dates 16-OCT-2006 (Created)
27-OCT-2018 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS00061; ADH_SHORT
Name Short-chain dehydrogenases/reductases family
Function Undefined.

Propagated annotation [?]


Description [?]

+ AltName: Full=Alcohol dehydrogenase; EC=1.1.1.1;

Comments [?]

Catalytic activity Reaction=a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH; Xref=Rhea:RHEA:10736, ChEBI:CHEBI:15378, ChEBI:CHEBI:15734, ChEBI:CHEBI:17478, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1;.
Reaction=a secondary alcohol + NAD(+) = a ketone + H(+) + NADH; Xref=Rhea:RHEA:10740, ChEBI:CHEBI:15378, ChEBI:CHEBI:17087, ChEBI:CHEBI:35681, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1;.

Features [?]

From: PS00061
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     3     3       Proton acceptor        

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example P48814 (ADH1_CERCA)
Scope
Eukaryota
Bacteria
Viruses

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]