ProRule PRU10018
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU10018 |
| Accession | PRU10018 |
| Dates | 16-OCT-2006 (Created)
3-SEP-2024 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS00094; C5_MTASE_1 |
Name | C-5 cytosine-specific DNA methylases active site |
| Function | Undefined |
| Scope(s) |
Eukaryota Bacteria Archaea Viruses |
| Example(s) | P25262 (MTB1_HERAU); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + AltName: Full=DNA (cytosine-5-)-methyltransferase; EC=2.1.1.37; |
Comments
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| CATALYTIC ACTIVITY | Reaction=a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5- methyl-2'-deoxycytidine in DNA + S-adenosyl-L-homocysteine + H(+); Xref=Rhea:RHEA:13681, Rhea:RHEA-COMP:11369, Rhea:RHEA-COMP:11370, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:85452, ChEBI:CHEBI:85454; EC=2.1.1.37; |
Features
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| From: PS00094 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 5 | 5 | ||||||||||
Additional information
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| Size range | unlimited amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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