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annotation rule: PRU10027

General rule information [?]

Accession PRU10027
Dates 16-OCT-2006 (Created)
27-OCT-2018 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS00108; PROTEIN_KINASE_ST
Name Serine/Threonine protein kinases active-site
Function Undefined.

Propagated annotation [?]


Description [?]

+ AltName: Full=Receptor protein-tyrosine kinase; EC=2.7.10.1;

Comments [?]

Catalytic activity Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L- tyrosyl-[protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858, ChEBI:CHEBI:82620, ChEBI:CHEBI:456216; EC=2.7.10.1;.

Features [?]

From: PS00108
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     3     3       Proton acceptor        

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example P00546 (CDK1_YEAST)
Scope
Eukaryota
Bacteria
Viruses

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.


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UniProtKB rule member sequences [?]