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ProRule PRU10085


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PURL: https://purl.expasy.org/prosite/rule/PRU10085
General rule information [?]

Accession PRU10085
Dates 16-OCT-2006 (Created)
28-APR-2022 (Last updated, Version 9)
Data class Domain;
Predictors PROSITE; PS00381; CLP_PROTEASE_SER
Name Endopeptidase Clp serine active site
Function Undefined
Scope(s) Eukaryota
Bacteria
Example(s) Q9K709 (CLPP1_HALH5);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + AltName: Full=Endopeptidase Clp;
                 EC=3.4.21.92;

Comments [?]

CATALYTIC ACTIVITY Reaction=Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr- Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).; EC=3.4.21.92;

Features [?]

From: PS00381
Key From To Description Tag Condition FTGroup
ACT_SITE 6 6

Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]