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annotation rule: PRU10086

General rule information [?]

Accession PRU10086
Dates 16-OCT-2006 (Created)
22-NOV-2019 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS00382; CLP_PROTEASE_HIS
Name Endopeptidase Clp histidine active site
Function Undefined.

Propagated annotation [?]


Description [?]

+ AltName: Full=Endopeptidase Clp; EC 3.4.21.92;

Comments [?]

Catalytic activity Reaction=Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).; EC=3.4.21.92;

Features [?]

From: PS00382
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     6     6                

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q81PL4 (CLPP1_BACAN)
Scope
Eukaryota
Bacteria

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]