ProRule PRU10140

General rule information [?]

Accession PRU10140
Dates 29-OCT-2018 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS60032; GH9_1
Name Glycosyl hydrolases family 9 (GH9) active site D
Function Three conserved regions in these enzymes are centered on conserved residues which have been shown to be important for the catalytic activity. The first region contains the characteristic DAGD motif, where the C-terminal D acts as the catalytic base that extracts a proton from the nucleophilic water.
Scope(s) Eukaryota
Example(s) O81416 (GUN17_ARATH);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=3.2.1.-;

Comments [?]

SIMILARITYBelongs to the glycosyl hydrolase 9 (cellulase E) family.

Keywords [?]

Gene Ontology [?]

GO:0004553; Molecular function:hydrolase activity, hydrolyzing O-glycosyl compounds

Features [?]

From: PS60032
Key From To Description Tag Condition FTGroup
ACT_SITE 9 9 /note="Nucleophile" D

Additional information [?]

Size range 18-18 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]