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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU10142


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU10142
General rule information [?]

Accession PRU10142
Dates 19-MAR-2021 (Created)
19-NOV-2022 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS00018; EF_HAND_1
Name EF-hand calcium-binding domain
Function Many calcium-binding proteins belong to the same evolutionary family and share a type of calcium-binding domain known as the EF-hand.
Scope(s) Eukaryota
Bacteria
Viruses
Example(s) P06702;

Propagated annotation [?]

Keywords [?]

Metal-binding
Calcium

Gene Ontology [?]

GO:0005509; Molecular function:calcium ion binding

Features [?]

From: PS00018
Key From To Description Tag Condition FTGroup
BINDING 1 1 /ligand="Ca(2+)"
/ligand_id="ChEBI:CHEBI:29108"
/ligand_label="#1"
BINDING 3 3 /ligand="Ca(2+)"
/ligand_id="ChEBI:CHEBI:29108"
/ligand_label="#1"
BINDING 5 5 /ligand="Ca(2+)"
/ligand_id="ChEBI:CHEBI:29108"
/ligand_label="#1"
BINDING 7 7 /ligand="Ca(2+)"
/ligand_id="ChEBI:CHEBI:29108"
/ligand_label="#1"
BINDING 10 10 /ligand="Ca(2+)"
/ligand_id="ChEBI:CHEBI:29108"
/ligand_label="#1"

Additional information [?]

Size range 11 amino acids
Related rules None
Fusion None
Repeats 1-8
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]