We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU10143
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU10143
General rule information
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| Accession | PRU10143 |
| Dates | 31-JAN-2023 (Created)
31-JAN-2023 (Last updated, Version 2) |
| Data class | Domain; |
| Predictors |
PROSITE; PS00430; TONB_DEPENDENT_REC_1 |
Name | TonB-dependent receptor (TBDR) proteins |
| Function | The C-terminal domain (CTD) of TonB protein has a globular structure of ~100 residues and interacts with a conserved TonB box motif located at the N-terminus of TBDRs, which likely induces structural changes in the outer membrane transporters. |
| Scope(s) |
Bacteria Pseudomonadota |
| Example(s) | Q9KVI9; |
Propagated annotation
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Keywords
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| case <AnyFeature:PS52016> | |
| TonB box | |
Features
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| From: PS00430 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOTIF | 2 | to | /note="TonB box #" | |||||||||
| end case | ||||||||||||
Additional information
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| Size range | 24-122 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [119] Eukaryota [3] Viruses [2] All [ 124 ]
- Retrieve set of proteins with 3D structure for this domain