ProRule PRU00824
General rule information
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| Accession | PRU00824 |
| Dates | 20-JUL-2010 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51491; TAU_MAP_2 |
Name | Tau and MAP proteins tubulin-binding repeat |
| Function | The C-terminal region of a subset of Microtubule Associated Proteins (MAPs) contain three or four tandem repeats of a conserved domain of about thirty amino acid residues which is implicated in tubulin- binding and which seems to have a stiffening effect on microtubules. |
| Scope(s) |
Eukaryota Eutheria |
| Example(s) | Q5S6V2 (TAU_PONPY); |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0005874; Cellular component:microtubule |
| GO:0007026; Biological process:negative regulation of microtubule depolymerization |
Cross-references
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| PROSITE | PS00229; TAU_MAP_1; 1; |
Features
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| From: PS51491 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REPEAT | from | to | /note="Tau/MAP #" | |||||||||
Additional information
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| Size range | 21-42 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 3-4 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [19] All [ 19 ]
- Retrieve set of proteins with 3D structure for this domain