Entry: PS00074

General information about the entry

Entry name [info] GLFV_DEHYDROGENASE
Accession [info] PS00074
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); NOV-1997 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00071
Associated ProRule [info] PRU10011

Name and characterization of the entry

Description [info] Glu / Leu / Phe / Val dehydrogenases active site.
Pattern [info]
[LIV]-x(2)-G-G-[SAG]-K-x-[GV]-x(3)-[DNST]-[PL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 103 in 103 different sequences
Number of true positive hits 100 in 100 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 10
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 97.09 %
Recall (true positives / (true positives + false negatives)) 90.91 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
100 sequences

DHE1_ARATH  (Q43314), DHE2_ARATH  (Q38946), DHE2_BACFR  (P94316), 
DHE2_BACSU  (P39633), DHE2_CLOSY  (P24295), DHE2_HALSI  (P29051), 
DHE2_NEUCR  (P00365), DHE2_PEPAS  (P28997), DHE2_PEPDI  (P27346), 
DHE2_PORG3  (B2RKJ1), DHE2_PORGI  (P0C934), DHE2_STAAC  (Q5HHC7), 
DHE2_STAAM  (Q99VD0), DHE2_STAAN  (Q7A6H8), DHE2_STAAR  (Q6GID0), 
DHE2_STAAS  (Q6GAW8), DHE2_STAAW  (Q7A1B9), DHE2_SULSO  (P80053), 
DHE2_YEAST  (P33327), DHE3_AERPE  (Q9YC65), DHE3_ARATH  (Q9S7A0), 
DHE3_BACTN  (P94598), DHE3_BOVIN  (P00366), DHE3_CHICK  (P00368), 
DHE3_DICDI  (Q54KB7), DHE3_DROME  (P54385), DHE3_HUMAN  (P00367), 
DHE3_MAIZE  (Q43260), DHE3_MOUSE  (P26443), DHE3_PYRAB  (Q47950), 
DHE3_PYREN  (Q47951), DHE3_PYRFU  (P80319), DHE3_PYRHO  (P0CL73), 
DHE3_PYRHR  (P0CL72), DHE3_RAT    (P10860), DHE3_SOLLC  (P93541), 
DHE3_THEKO  (O59650), DHE3_THELN  (Q56304), DHE3_THEMA  (P96110), 
DHE3_THEPR  (O74024), DHE3_VITVI  (P52596), DHE4_AGABI  (P54387), 
DHE4_BOTFU  (O93934), DHE4_CHLSO  (P28998), DHE4_COREF  (Q8RQP4), 
DHE4_CORGL  (P31026), DHE4_ECOLI  (P00370), DHE4_EMENI  (P18819), 
DHE4_GIAIN  (P28724), DHE4_GIBFU  (Q96VJ7), DHE4_GORGO  (Q64I01), 
DHE4_HAEIN  (P43793), DHE4_HALSA  (Q9HRM7), DHE4_HALSI  (Q5MBG2), 
DHE4_HEBCY  (Q96UJ9), DHE4_HELPJ  (Q9ZKD8), DHE4_HELPY  (P55990), 
DHE4_HUMAN  (P49448), DHE4_HYLLA  (Q64HZ9), DHE4_LACBS  (P54388), 
DHE4_NEUCR  (P00369), DHE4_NEUIN  (Q9HGU4), DHE4_NEUSI  (Q9HGU3), 
DHE4_PANTR  (Q64HZ8), DHE4_PENCH  (Q9URS1), DHE4_PONPY  (Q64I00), 
DHE4_PRERU  (P95544), DHE4_PSYT1  (Q9S1F9), DHE4_SACU7  (Q8TFF6), 
DHE4_SALTI  (Q8Z6F6), DHE4_SALTY  (P15111), DHE4_SCHOC  (P29507), 
DHE4_SCHPO  (P78804), DHE4_SULSH  (P39475), DHE4_SYNY3  (P54386), 
DHE4_TUBBO  (Q9HFR6), DHE4_UNKP   (P14657), DHE4_YEAST  (P07262), 
DHE5_YEAST  (P39708), DHEB_HALSA  (P0DMG4), DHEB_HALSI  (P0DMG3), 
DHEB_NICPL  (Q9LEC8), DHE_HALSA   (Q9HQE1), DHE_HALSI   (F2Z610), 
DHLE_BACCE  (P0A393), DHLE_BACCR  (P0A392), DHLE_BACLI  (Q53560), 
DHLE_BACSU  (P54531), DHLE_GEOSE  (P13154), DHLE_THEIN  (Q60030), 
DHPH_BACBA  (Q59224), DHPH_LYSSH  (P23307), DHPH_SPOUR  (P97014), 
DHPH_THEIN  (P22823), GUDB_BACSU  (P50735), VDH_STRAL   (O69056), 
VDH_STRAM   (P42709), VDH_STRCM   (Q53872), VDH_STRCO   (Q06539), 
VDH_STRFR   (P40176)
» More

UniProtKB/Swiss-Prot
False negative sequences
10 sequences

DHE2_ACHKL  (P41755), DHE2_MYCS2  (A0R1C2), DHE2_MYCTU  (O53203), 
DHE2_PSEAE  (Q9HZE0), DHE2_PYRCJ  (A3MUY9), DHE3_CHAAC  (P82264), 
DHE3_RHISN  (Q53199), DHE4_PYRCJ  (A3MWK6), DHEA_NICPL  (O04937), 
GLUD2_DICDI (Q54VI3)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
4 sequences

DHE2_THUTH  (P20016), DHE3_ELEEL  (P28270), DHE3_PIG    (P42174), 
DHE3_PYRWO  (Q09115)
» More

UniProtKB/Swiss-Prot
False positive sequences
3 sequences

CHM4C_DANRE (Q6IQ73), IRC3_YEAST  (Q06683), SEC24_DICDI (Q54U61)

		
PDB
[Detailed view]
29 PDB

1AUP; 1B26; 1B3B; 1BGV; 1BVU; 1EUZ; 1GTM; 1HRD; 1HWY; 1HWZ; 1K89; 1L1F; 1NQT; 1NR1; 1NR7; 2TMG; 2YFH; 2YFQ; 3ETD; 3ETE; 3ETG; 3K8Z; 3K92; 3MVO; 3MVQ; 3MW9; 3QMU; 3SBO; 4BHT
» More

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