Entry: PS00074

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General information about the entry

Entry name [info] GLFV_DEHYDROGENASE
Accession [info] PS00074
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); NOV-1997 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00071
Associated ProRule [info] PRU10011

Name and characterization of the entry

Description [info] Glu / Leu / Phe / Val dehydrogenases active site.
Pattern [info]
[LIV]-x(2)-G-G-[SAG]-K-x-[GV]-x(3)-[DNST]-[PL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 103 in 103 different sequences
Number of true positive hits 100 in 100 different sequences
Number of 'unknown' hits
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 8
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 97.09 %
Recall (true positives / (true positives + false negatives)) 92.59 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
100 sequences

DHE1_ARATH  (Q43314), DHE2_ARATH  (Q38946), DHE2_BACFR  (P94316), 
DHE2_BACSU  (P39633), DHE2_CLOSY  (P24295), DHE2_HALSI  (P29051), 
DHE2_NEUCR  (P00365), DHE2_PEPAS  (P28997), DHE2_PEPDI  (P27346), 
DHE2_PORG3  (B2RKJ1), DHE2_PORGI  (P0C934), DHE2_STAAC  (Q5HHC7), 
DHE2_STAAM  (Q99VD0), DHE2_STAAN  (Q7A6H8), DHE2_STAAR  (Q6GID0), 
DHE2_STAAS  (Q6GAW8), DHE2_STAAW  (Q7A1B9), DHE2_SULSO  (P80053), 
DHE2_YEAST  (P33327), DHE3_AERPE  (Q9YC65), DHE3_ARATH  (Q9S7A0), 
DHE3_BACTN  (P94598), DHE3_BOVIN  (P00366), DHE3_CHICK  (P00368), 
DHE3_DICDI  (Q54KB7), DHE3_DROME  (P54385), DHE3_HUMAN  (P00367), 
DHE3_MAIZE  (Q43260), DHE3_MOUSE  (P26443), DHE3_PYRAB  (Q47950), 
DHE3_PYREN  (Q47951), DHE3_PYRFU  (P80319), DHE3_PYRHO  (P0CL73), 
DHE3_PYRHR  (P0CL72), DHE3_RAT    (P10860), DHE3_SOLLC  (P93541), 
DHE3_THEKO  (O59650), DHE3_THELN  (Q56304), DHE3_THEMA  (P96110), 
DHE3_THEPR  (O74024), DHE3_VITVI  (P52596), DHE4_AGABI  (P54387), 
DHE4_BOTFU  (O93934), DHE4_CHLSO  (P28998), DHE4_COREF  (Q8RQP4), 
DHE4_CORGL  (P31026), DHE4_ECOLI  (P00370), DHE4_EMENI  (P18819), 
DHE4_GIAIN  (P28724), DHE4_GIBFU  (Q96VJ7), DHE4_GORGO  (Q64I01), 
DHE4_HAEIN  (P43793), DHE4_HALSA  (Q9HRM7), DHE4_HALSI  (Q5MBG2), 
DHE4_HEBCY  (Q96UJ9), DHE4_HELPJ  (Q9ZKD8), DHE4_HELPY  (P55990), 
DHE4_HUMAN  (P49448), DHE4_HYLLA  (Q64HZ9), DHE4_LACBS  (P54388), 
DHE4_NEUCR  (P00369), DHE4_NEUIN  (Q9HGU4), DHE4_NEUSI  (Q9HGU3), 
DHE4_PANTR  (Q64HZ8), DHE4_PENCH  (Q9URS1), DHE4_PONPY  (Q64I00), 
DHE4_PRERU  (P95544), DHE4_PSYT1  (Q9S1F9), DHE4_SACU7  (Q8TFF6), 
DHE4_SALTI  (Q8Z6F6), DHE4_SALTY  (P15111), DHE4_SCHOC  (P29507), 
DHE4_SCHPO  (P78804), DHE4_SULSH  (P39475), DHE4_SYNY3  (P54386), 
DHE4_TUBBO  (Q9HFR6), DHE4_UNKP   (P14657), DHE4_YEAST  (P07262), 
DHE5_YEAST  (P39708), DHEB_HALSA  (P0DMG4), DHEB_HALSI  (P0DMG3), 
DHEB_NICPL  (Q9LEC8), DHE_HALSA   (Q9HQE1), DHE_HALSI   (F2Z610), 
DHLE_BACCE  (P0A393), DHLE_BACCR  (P0A392), DHLE_BACLI  (Q53560), 
DHLE_BACSU  (P54531), DHLE_GEOSE  (P13154), DHLE_THEIN  (Q60030), 
DHPH_BACBA  (Q59224), DHPH_LYSSH  (P23307), DHPH_SPOUR  (P97014), 
DHPH_THEIN  (P22823), GUDB_BACSU  (P50735), VDH_STRAL   (O69056), 
VDH_STRAM   (P42709), VDH_STRCM   (Q53872), VDH_STRCO   (Q06539), 
VDH_STRFR   (P40176)
» More

UniProtKB/Swiss-Prot
False negative sequences
8 sequences

DHE2_ACHKL  (P41755), DHE2_MYCS2  (A0R1C2), DHE2_MYCTU  (O53203), 
DHE2_PSEAE  (Q9HZE0), DHE3_CHAAC  (P82264), DHE3_RHISN  (Q53199), 
DHEA_NICPL  (O04937), GLUD2_DICDI (Q54VI3)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
4 sequences

DHE2_THUTH  (P20016), DHE3_ELEEL  (P28270), DHE3_PIG    (P42174), 
DHE3_PYRWO  (Q09115)
» More

UniProtKB/Swiss-Prot
False positive sequences
3 sequences

CHM4C_DANRE (Q6IQ73), IRC3_YEAST  (Q06683), SEC24_DICDI (Q54U61)

		
PDB
[Detailed view]
29 PDB

1AUP; 1B26; 1B3B; 1BGV; 1BVU; 1EUZ; 1GTM; 1HRD; 1HWY; 1HWZ; 1K89; 1L1F; 1NQT; 1NR1; 1NR7; 2TMG; 2YFH; 2YFQ; 3ETD; 3ETE; 3ETG; 3K8Z; 3K92; 3MVO; 3MVQ; 3MW9; 3QMU; 3SBO; 4BHT
» More

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