Entry: PS00074
General information about the entry
Entry nameGLFV_DEHYDROGENASE
Accession numberPS00074
Entry typePATTERN
DateAPR-1990 (CREATED); NOV-1997 (DATA UPDATE); DEC-2011 (INFO UPDATE).
PROSITE DocumentationPDOC00071
Associated ProRulePRU10011
Name and characterization of the entry
DescriptionGlu / Leu / Phe / Val dehydrogenases active site.
Pattern[LIV]-x(2)-G-G-[SAG]-K-x-[GV]-x(3)-[DNST]-[PL].
Numerical results
  • UniProtKB/Swiss-Prot release number: 01, total number of sequence entries in that release: 534242.
  • Total number of hits in UniProtKB/Swiss-Prot: 98 hits in 98 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 95 hits in 95 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 3 hits in 3 different sequences
  • Number of known missed hits: 6
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 4
  • Precision (true hits / (true hits + false positives)): 96.94 %
  • Recall (true hits / (true hits + false negatives)): 94.06 %
Comments
  • Taxonomic range: Archaebacteria, Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 6,active_site
  • VERSION: 1
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
DHE1_ARATH  (Q43314), DHE2_ARATH  (Q38946), DHE2_BACFR  (P94316), 
DHE2_BACSU  (P39633), DHE2_CLODI  (P27346), DHE2_CLOSY  (P24295), 
DHE2_NEUCR  (P00365), DHE2_PEPAS  (P28997), DHE2_PORG3  (B2RKJ1), 
DHE2_PORGI  (P0C934), DHE2_STAAC  (Q5HHC7), DHE2_STAAM  (Q99VD0), 
DHE2_STAAN  (Q7A6H8), DHE2_STAAR  (Q6GID0), DHE2_STAAS  (Q6GAW8), 
DHE2_STAAW  (Q7A1B9), DHE2_SULSO  (P80053), DHE2_YEAST  (P33327), 
DHE3_AERPE  (Q9YC65), DHE3_ARATH  (Q9S7A0), DHE3_BACTN  (P94598), 
DHE3_BOVIN  (P00366), DHE3_CHICK  (P00368), DHE3_DICDI  (Q54KB7), 
DHE3_DROME  (P54385), DHE3_HUMAN  (P00367), DHE3_MAIZE  (Q43260), 
DHE3_MOUSE  (P26443), DHE3_PYRAB  (Q47950), DHE3_PYREN  (Q47951), 
DHE3_PYRFU  (P80319), DHE3_PYRHO  (P0CL73), DHE3_PYRHR  (P0CL72), 
DHE3_PYRKO  (O59650), DHE3_RAT    (P10860), DHE3_SOLLC  (P93541), 
DHE3_THELI  (Q56304), DHE3_THEMA  (P96110), DHE3_THEPR  (O74024), 
DHE3_VITVI  (P52596), DHE41_HALSI (P29051), DHE42_HALSA (Q9HSM4), 
DHE4_AGABI  (P54387), DHE4_BOTFU  (O93934), DHE4_CHLSO  (P28998), 
DHE4_COREF  (Q8RQP4), DHE4_CORGL  (P31026), DHE4_ECOLI  (P00370), 
DHE4_EMENI  (P18819), DHE4_GIAIN  (P28724), DHE4_GIBFU  (Q96VJ7), 
DHE4_GORGO  (Q64I01), DHE4_HAEIN  (P43793), DHE4_HEBCY  (Q96UJ9), 
DHE4_HELPJ  (Q9ZKD8), DHE4_HELPY  (P55990), DHE4_HUMAN  (P49448), 
DHE4_HYLLA  (Q64HZ9), DHE4_LACBS  (P54388), DHE4_NEUCR  (P00369), 
DHE4_NEUIN  (Q9HGU4), DHE4_NEUSI  (Q9HGU3), DHE4_PANTR  (Q64HZ8), 
DHE4_PENCH  (Q9URS1), DHE4_PONPY  (Q64I00), DHE4_PRERU  (P95544), 
DHE4_PSYT1  (Q9S1F9), DHE4_SACBA  (Q8TFF6), DHE4_SALTI  (Q8Z6F6), 
DHE4_SALTY  (P15111), DHE4_SCHOC  (P29507), DHE4_SCHPO  (P78804), 
DHE4_SULSH  (P39475), DHE4_SYNY3  (P54386), DHE4_TUBBO  (Q9HFR6), 
DHE4_UNKP   (P14657), DHE4_YEAST  (P07262), DHE5_YEAST  (P39708), 
DHEB_NICPL  (Q9LEC8), DHLE_BACCE  (P0A393), DHLE_BACCR  (P0A392), 
DHLE_BACLI  (Q53560), DHLE_BACSU  (P54531), DHLE_GEOSE  (P13154), 
DHLE_THEIN  (Q60030), DHPH_BACBA  (Q59224), DHPH_LYSSH  (P23307), 
DHPH_SPOUR  (P97014), DHPH_THEIN  (P22823), GUDB_BACSU  (P50735), 
VDH_STRAL   (O69056), VDH_STRAM   (P42709), VDH_STRCM   (Q53872), 
VDH_STRCO   (Q06539), VDH_STRFR   (P40176)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
DHE2_ACHKL  (P41755), DHE2_PSEAE  (Q9HZE0), DHE3_CHAAC  (P82264), 
DHE3_RHISN  (Q53199), DHEA_NICPL  (O04937), GLUD2_DICDI (Q54VI3)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
DHE2_THUTH  (P20016), DHE3_ELEEL  (P28270), DHE3_PIG    (P42174), 
DHE3_PYRWO  (Q09115)
False positive hits (sequences which do not belong to the set under consideration):
CHM4C_DANRE (Q6IQ73), IRC3_YEAST  (Q06683), SEC24_DICDI (Q54U61)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1AUP; 1B26; 1B3B; 1BGV; 1BVU; 1EUZ; 1GTM; 1HRD; 1HWY; 1HWZ; 1K89; 1L1F; 1NQT; 1NR1; 1NR7; 2TMG; 2YFQ; 3ETD; 3ETE; 3ETG; 3K8Z; 3K92; 3MVO; 3MVQ; 3MW9; 3QMU;

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