Due to maintenance work, this service may be impaired on Sunday February 1st between 12.00 pm and 06.00 pm CEST.
ScanProsite tool
ScanProsite
This form allows you to scan proteins for matches against the PROSITE collection of motifs as well as against your own patterns.

Option 1 - Submit PROTEIN sequences to scan them against the PROSITE collection of motifs.
Option 2 - Submit MOTIFS to scan them against a PROTEIN sequence database.
Option 3 - Submit PROTEIN sequences and MOTIFS to scan them against each other.



STEP 1 - Submit PROTEIN sequences [help]

Submit PROTEIN sequences (max. 10) Examples
Submit a PROTEIN database (max. 16MB) for repeated scans (The data will be stored on our server for 1 month).


Supported input:
If you already have a code for your database, enter the code:
Otherwise, upload your database as a FASTA file to obtain a code

STEP 2 - Select options [help]

Exclude motifs with a high probability of occurrence from the scan
Exclude profiles from the scan
Run the scan at high sensitivity (show weak matches for profiles)
STEP 1 - Enter a MOTIF or a combination of MOTIFS Examples [help]


Supported input:
  • A PROSITE accession e.g. PS50240 or identifier e.g. TRYPSIN_DOM
  • Your own pattern e.g. P-x(2)-G-E-S-G(2)-[AS]
  • A combination of PROSITE accessions/identifiers e.g. PS50240 and PS50068, e.g. PS50240 and not ( PS00134 or PS00135 )
  • A combination of PROSITE accessions/identifiers and your own pattern e.g. PS50240 and P-x(2)-G-E-S-G(2)-[AS]
      » More
» Options [help]

STEP2 - Select a PROTEIN sequence database [help]

UniProtKB
      Swiss-Prot Include splice variants
      TrEMBL

PDB
Your protein database
       If you already have a code for your database, enter the code:
       Otherwise, upload your database as a FASTA file to obtain a code

Randomized UniProtKB/Swiss-Prot
[help]
      reversed
      window20

Exclude fragments (concerns UniProtKB only)
» Filters [help]
  • On length >= than:
  • On length <= than:
  • On taxonomy:   any taxonomical term e.g. Homo sapiens, e.g. Fungi; Arthropoda or corresponding TaxID e.g. 9606, e.g. 4751; 6656
  • On description: e.g. protease
  • On Tissue expression (Bgee data):
    (only on Human, Xenopus, Mouse and Zebrafish; adult stage)
    N.B. Does not consider splice variants of UniProtKB/Swiss-Prot.
STEP 1 - Submit PROTEIN sequences [help]

Submit PROTEIN sequences (max. 1'000) Examples
Submit a PROTEIN database (max. 16MB) for repeated scans (The data will be stored on our server for 1 month).


Supported input:
If you already have a code for your database, enter the code:
Otherwise, upload your database as a FASTA file to obtain a code

STEP 2 - Enter a MOTIF or a combination of MOTIFS Examples [help]


Supported input:
  • A PROSITE accession e.g. PS50240 or identifier e.g. TRYPSIN_DOM
  • Your own pattern e.g. P-x(2)-G-E-S-G(2)-[AS]
  • A combination of PROSITE accessions/identifiers e.g. PS50240 and PS50068, e.g. PS50240 and not ( PS00134 or PS00135 )
  • A combination of PROSITE accessions/identifiers and your own pattern e.g. PS50240 and P-x(2)-G-E-S-G(2)-[AS]
» More
» Options [help]
  • Profile option
  • Pattern options
    • Number of X characters in a scanned sequence that can be matched by a conserved position in a pattern:
    • Match mode:

STEP 3 - Select output options and submit your job

Output format:
Maximum number of displayed matches: If you select 100'000, results are returned by email and not all output formats are available.
Retrieve complete sequences: If you choose this option, not all output formats are available.

Receive your results by email
Email: Note that not all output formats are available for results returned by email.
Job title: If available, the job title will be included in the subject of the results email.