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Database of protein domains, families and functional sites

PROSITE consists of documentation entries describing protein domains, families and functional sites as well as associated patterns and profiles to identify them [More details / References / Commercial users].
PROSITE is complemented by ProRule, a collection of rules based on profiles and patterns, which increases the discriminatory power of profiles and patterns by providing additional information about functionally and/or structurally critical amino acids [More details].

Release 20.81, of 11-May-2012 (1644 documentation entries, 1308 patterns, 1034 profiles and 1038 ProRule)
PROSITE access
e.g. PDOC00022, PS50089, SH3, zinc finger

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PROSITE tools
Scan a sequence against PROSITE patterns and profiles - quick scan
(Output includes graphical view and feature detection)
scanview
Enter your sequence or a UniProtKB (Swiss-Prot or TrEMBL) ID or AC [ help ]:


 exclude patterns with a high probability of occurrence
  • ScanProsite -  advanced scan
  • PRATT -  allows to interactively generate conserved patterns from a series of unaligned proteins.
  • MyDomains - Image Creatornew -  allows to generate custom domain figures.
    scanview