Database of protein domains, families and functional sites

PROSITE consists of documentation entries describing protein domains, families and functional sites as well as associated patterns and profiles to identify them [More... / References / Commercial users].
PROSITE is complemented by ProRule, a collection of rules based on profiles and patterns, which increases the discriminatory power of profiles and patterns by providing additional information about functionally and/or structurally critical amino acids [More...].

Release 20.93, of 24-Apr-2013 (1664 documentation entries, 1308 patterns, 1058 profiles and 1058 ProRule)
PROSITE access
e.g. PDOC00022, PS50089, SH3, zinc finger
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PROSITE tools
Scan a sequence against PROSITE patterns and profiles - quick scan

(Output includes graphical view and feature detection)

scanview

Enter your sequence(s) or (a) UniProtKB (Swiss-Prot or TrEMBL) AC or ID [ Help ]:


 exclude patterns with a high probability of occurrence
  • ScanProsite -  advanced scan
  • PRATT -  allows to interactively generate conserved patterns from a series of unaligned proteins.
  • MyDomains - Image Creator -  allows to generate custom domain figures.
scanview