Entry: PS00114

General information about the entry
Entry name PRPP_SYNTHASE
Accession number PS00114
Entry type PATTERN
Date APR-1990 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00105
Name and characterization of the entry
DescriptionPhosphoribosyl pyrophosphate synthase signature.
Pattern D-[LIM]-H-[SANDT]-x-[QS]-[IMSTAVF]-[QMLPH]-[GA]-[FY]-F-x(2)-P- [LIVMFCT]-D.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 170 hits in 170 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 170 hits in 170 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 32
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 84.16 %
Comments
  • Taxonomic range: Archaea, Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 1,magnesium(?)
  • `Interesting' site in the pattern: 3,magnesium(?)
  • `Interesting' site in the pattern: 15,magnesium(?)
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
KPR1_CANAX  (P46585), KPR1_SCHPO  (P41831), KPR1_YEAST  (P32895), 
KPR2_SCHPO  (O94413), KPR2_YEAST  (P38620), KPR3_YEAST  (P38689), 
KPR4_YEAST  (P38063), KPR5_SCHPO  (P87171), KPR5_YEAST  (Q12265), 
KPRS1_ARATH (Q42581), KPRS1_ENTFA (Q82ZA5), KPRS1_LACLA (Q9CHB8), 
KPRS1_LACPL (Q88Z84), KPRS1_LISIN (Q92F68), KPRS1_LISIV (Q83YI7), 
KPRS1_LISMF (Q724L4), KPRS1_LISMO (Q48793), KPRS1_LISWE (Q83TK1), 
KPRS1_ORYSJ (Q6Z2L5), KPRS1_SPIOL (Q9XG98), KPRS1_STRA3 (Q8E7X8), 
KPRS1_STRA5 (Q8E2H0), KPRS1_STRMU (Q8DWM2), KPRS1_STRP1 (P65243), 
KPRS1_STRP3 (P0DB98), KPRS1_STRP6 (Q5XEL0), KPRS1_STRP8 (P65245), 
KPRS1_STRPN (P65239), KPRS1_STRPQ (P0DB99), KPRS1_STRR6 (P65240), 
KPRS2_ARATH (Q42583), KPRS2_ENTFA (Q832Z5), KPRS2_LACLA (Q9CEI4), 
KPRS2_LACPL (Q88VA5), KPRS2_LISIN (Q92EF1), KPRS2_LISMF (Q723E1), 
KPRS2_LISMO (Q8Y9L8), KPRS2_ORYSJ (Q69XQ6), KPRS2_SPIOL (Q9XG99), 
KPRS2_STRA3 (Q8E568), KPRS2_STRA5 (Q8DZK4), KPRS2_STRMU (Q8DU94), 
KPRS2_STRP1 (Q99ZR0), KPRS2_STRP3 (P0DC00), KPRS2_STRP6 (Q5XC85), 
KPRS2_STRP8 (Q8P137), KPRS2_STRPN (P65241), KPRS2_STRPQ (P0DC01), 
KPRS2_STRR6 (P65242), KPRS5_ARATH (O64888), KPRS_AGRT5  (Q8UDA9), 
KPRS_BACAN  (Q81VZ0), KPRS_BACCL  (P42816), KPRS_BACCR  (Q81J97), 
KPRS_BACHD  (Q9KGJ5), KPRS_BACSU  (P14193), KPRS_BAUCH  (Q1LTH2), 
KPRS_BIFLO  (Q8G5P2), KPRS_BLOFL  (Q7VR76), KPRS_BORBR  (Q7WNY4), 
KPRS_BORPA  (Q7W181), KPRS_BORPE  (Q7VUH1), KPRS_BRAJA  (Q89DJ1), 
KPRS_BRUME  (Q8YIG1), KPRS_BRUSU  (Q8FZF0), KPRS_BUCAI  (P57266), 
KPRS_BUCAP  (Q8K9X2), KPRS_BUCBP  (P59512), KPRS_CAMJE  (Q9PP15), 
KPRS_CAUCN  (B8GZV1), KPRS_CAUCR  (Q9AAV6), KPRS_CHLTE  (Q8KCQ2), 
KPRS_CHRVO  (Q7NQS9), KPRS_CLOAB  (Q97E93), KPRS_CLOPE  (Q8XHJ4), 
KPRS_CLOTE  (Q899I8), KPRS_CORAM  (O33924), KPRS_COREF  (Q8FQV2), 
KPRS_CORGL  (Q8NRU9), KPRS_COXBU  (Q83AQ1), KPRS_DESPS  (Q6AJL7), 
KPRS_ECO57  (P0A719), KPRS_ECOL6  (P0A718), KPRS_ECOLI  (P0A717), 
KPRS_FUSNN  (Q8RHM2), KPRS_GLOVI  (Q7NM67), KPRS_GRABC  (Q0BPP0), 
KPRS_HAEDU  (Q7VL55), KPRS_HAEIN  (P44328), KPRS_HELHP  (Q7VFY9), 
KPRS_HELPJ  (Q9ZLA1), KPRS_HELPY  (P56184), KPRS_HYPNA  (Q0C5A1), 
KPRS_LEPIC  (Q72V73), KPRS_LEPIN  (Q8EZN0), KPRS_MARMM  (Q0ARN5), 
KPRS_MARMS  (A6W1C7), KPRS_MYCBO  (P65233), KPRS_MYCGE  (P47304), 
KPRS_MYCLE  (Q9CD45), KPRS_MYCPN  (P75044), KPRS_MYCPU  (Q98R83), 
KPRS_MYCTU  (P65232), KPRS_NEIMA  (P65234), KPRS_NEIMB  (P65235), 
KPRS_NITEU  (Q82TQ4), KPRS_NOSS1  (Q8YN97), KPRS_OCEIH  (Q8EU34), 
KPRS_PASMU  (Q9CP22), KPRS_PHOLL  (Q7N590), KPRS_PORGI  (Q7MT83), 
KPRS_PROMA  (Q7VBH4), KPRS_PROMM  (Q7V6S2), KPRS_PROMP  (Q7V111), 
KPRS_PSEAE  (Q9HVC5), KPRS_PSEPK  (Q88PX6), KPRS_PSESM  (Q888C6), 
KPRS_RALSO  (Q8Y2E1), KPRS_RHILO  (Q98HW3), KPRS_RHIME  (Q92N73), 
KPRS_RHOBA  (Q7UPM4), KPRS_RHOSK  (B9KPJ0), KPRS_SALTI  (P0A1V7), 
KPRS_SALTY  (P0A1V6), KPRS_SHEON  (Q8EAQ9), KPRS_STAAC  (Q5HIH5), 
KPRS_STAAM  (P65236), KPRS_STAAN  (P65237), KPRS_STAAR  (Q6GJH1), 
KPRS_STAAS  (Q6GBY8), KPRS_STAAW  (P65238), KPRS_STAEQ  (Q5HRQ5), 
KPRS_STAES  (Q8CQU7), KPRS_STAHJ  (Q4L3F7), KPRS_STAS1  (Q49V09), 
KPRS_STRAW  (Q82HE7), KPRS_STRCO  (Q9K3U0), KPRS_SYNE7  (Q59988), 
KPRS_SYNPX  (Q7U7L5), KPRS_SYNY3  (Q55848), KPRS_THEAB  (B7IFM5), 
KPRS_THEMA  (Q9X1W3), KPRS_THETN  (Q8R753), KPRS_UREPA  (Q9PQV0), 
KPRS_VIBCH  (Q9KQ22), KPRS_VIBPA  (Q87RN8), KPRS_VIBVU  (Q8DFF5), 
KPRS_VIBVY  (Q7MMZ1), KPRS_WOLSU  (Q7M8J0), KPRS_XANAC  (Q8PNU0), 
KPRS_XANCP  (Q8PC63), KPRS_XYLFA  (Q9PA76), KPRS_XYLFT  (Q87A22), 
KPRS_YERPE  (Q8ZEY2), PRPS1_BOVIN (Q2HJ58), PRPS1_HUMAN (P60891), 
PRPS1_MACFA (Q4R4U3), PRPS1_MOUSE (Q9D7G0), PRPS1_PONAB (Q5RFJ7), 
PRPS1_RAT   (P60892), PRPS2_CHICK (Q5ZI49), PRPS2_HUMAN (P11908), 
PRPS2_MACFA (Q4R4R7), PRPS2_MOUSE (Q9CS42), PRPS2_PONAB (Q5R8F8), 
PRPS2_RAT   (P09330), PRPS2_XENLA (Q7ZXC9), PRPS2_XENTR (Q5XGI0), 
PRPS3_HUMAN (P21108), PRPSA_DICDI (Q54PA9)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
KPRH_STRCO  (Q9EWS0), KPRS1_ARCFU (O29666), KPRS2_ARCFU (O28853), 
KPRS3_ARATH (Q93Z66), KPRS3_ORYSJ (Q8S2E5), KPRS3_SPIOL (Q9XGA0), 
KPRS4_ARATH (Q680A5), KPRS4_ORYSJ (Q6ZFT5), KPRS4_SPIOL (Q9XGA1), 
KPRS_AERPE  (Q9YAW0), KPRS_AQUAE  (O67556), KPRS_DEIRA  (Q9RUD2), 
KPRS_HALS3  (B0R7B4), KPRS_HALSA  (Q9HN88), KPRS_METAC  (Q8TRK8), 
KPRS_METJA  (Q58761), KPRS_METKA  (Q8TUT6), KPRS_METMA  (Q8PUX3), 
KPRS_METS3  (A5UNK4), KPRS_METTH  (O26877), KPRS_PYRAB  (Q9UY08), 
KPRS_PYRAE  (Q8ZU24), KPRS_PYRFU  (Q8U458), KPRS_PYRHO  (O59586), 
KPRS_PYRKO  (O52958), KPRS_SULAC  (Q4J9A6), KPRS_SULSO  (Q97Z86), 
KPRS_SULTO  (Q973F3), KPRS_THEAC  (Q9HLV6), KPRS_THEVO  (Q97CA5), 
PRPSB_DICDI (Q75JN8), PRPSC_DICDI (Q54QU9)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1DKR; 1DKU; 1IBS; 2H06; 2H07; 2H08; 2HCR; 3EFH; 3S5J;

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View entry in raw text format (no links)
Direct ScanProsite submission


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