Entry: PS00114

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General information about the entry

Entry name [info] PRPP_SYNTHASE
Accession [info] PS00114
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); SEP-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00105

Name and characterization of the entry

Description [info] Phosphoribosyl pyrophosphate synthase signature.
Pattern [info]
D-[LIM]-H-[SANDT]-x-[QS]-[IMSTAVF]-[QMLPH]-[GA]-[FY]-F-x(2)-P-
[LIVMFCT]-D.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_10 which contains 546'790 sequence entries.


Total number of hits 171 in 171 different sequences
Number of true positive hits 171 in 171 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 32
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 84.24 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] magnesium(?) at position 1
Site [info] magnesium(?) at position 3
Site [info] magnesium(?) at position 15
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
171 sequences

KPR1_CANAX  (P46585), KPR1_SCHPO  (P41831), KPR1_YEAST  (P32895), 
KPR2_SCHPO  (O94413), KPR2_YEAST  (P38620), KPR3_YEAST  (P38689), 
KPR4_YEAST  (P38063), KPR5_SCHPO  (P87171), KPR5_YEAST  (Q12265), 
KPRS1_ARATH (Q42581), KPRS1_ENTFA (Q82ZA5), KPRS1_LACLA (Q9CHB8), 
KPRS1_LACPL (Q88Z84), KPRS1_LISIN (Q92F68), KPRS1_LISIV (Q83YI7), 
KPRS1_LISMF (Q724L4), KPRS1_LISMO (Q48793), KPRS1_LISWE (Q83TK1), 
KPRS1_ORYSJ (Q6Z2L5), KPRS1_SPIOL (Q9XG98), KPRS1_STRA3 (Q8E7X8), 
KPRS1_STRA5 (Q8E2H0), KPRS1_STRMU (Q8DWM2), KPRS1_STRP1 (P65243), 
KPRS1_STRP3 (P0DB98), KPRS1_STRP6 (Q5XEL0), KPRS1_STRP8 (P65245), 
KPRS1_STRPN (P65239), KPRS1_STRPQ (P0DB99), KPRS1_STRR6 (P65240), 
KPRS2_ARATH (Q42583), KPRS2_ENTFA (Q832Z5), KPRS2_LACLA (Q9CEI4), 
KPRS2_LACPL (Q88VA5), KPRS2_LISIN (Q92EF1), KPRS2_LISMF (Q723E1), 
KPRS2_LISMO (Q8Y9L8), KPRS2_ORYSJ (Q69XQ6), KPRS2_SPIOL (Q9XG99), 
KPRS2_STRA3 (Q8E568), KPRS2_STRA5 (Q8DZK4), KPRS2_STRMU (Q8DU94), 
KPRS2_STRP1 (Q99ZR0), KPRS2_STRP3 (P0DC00), KPRS2_STRP6 (Q5XC85), 
KPRS2_STRP8 (Q8P137), KPRS2_STRPN (P65241), KPRS2_STRPQ (P0DC01), 
KPRS2_STRR6 (P65242), KPRS5_ARATH (O64888), KPRS_AGRT5  (Q8UDA9), 
KPRS_BACAN  (Q81VZ0), KPRS_BACCL  (P42816), KPRS_BACCR  (Q81J97), 
KPRS_BACHD  (Q9KGJ5), KPRS_BACSU  (P14193), KPRS_BAUCH  (Q1LTH2), 
KPRS_BIFLO  (Q8G5P2), KPRS_BLOFL  (Q7VR76), KPRS_BORBR  (Q7WNY4), 
KPRS_BORPA  (Q7W181), KPRS_BORPE  (Q7VUH1), KPRS_BRADU  (Q89DJ1), 
KPRS_BRUME  (Q8YIG1), KPRS_BRUSU  (Q8FZF0), KPRS_BUCAI  (P57266), 
KPRS_BUCAP  (Q8K9X2), KPRS_BUCBP  (P59512), KPRS_CALS4  (Q8R753), 
KPRS_CAMJE  (Q9PP15), KPRS_CAUCN  (B8GZV1), KPRS_CAUCR  (Q9AAV6), 
KPRS_CHLTE  (Q8KCQ2), KPRS_CHRVO  (Q7NQS9), KPRS_CLOAB  (Q97E93), 
KPRS_CLOPE  (Q8XHJ4), KPRS_CLOTE  (Q899I8), KPRS_CORAM  (O33924), 
KPRS_COREF  (Q8FQV2), KPRS_CORGL  (Q8NRU9), KPRS_COXBU  (Q83AQ1), 
KPRS_DESPS  (Q6AJL7), KPRS_ECO57  (P0A719), KPRS_ECOL6  (P0A718), 
KPRS_ECOLI  (P0A717), KPRS_FUSNN  (Q8RHM2), KPRS_GLOVI  (Q7NM67), 
KPRS_GRABC  (Q0BPP0), KPRS_HAEDU  (Q7VL55), KPRS_HAEIN  (P44328), 
KPRS_HELHP  (Q7VFY9), KPRS_HELPJ  (Q9ZLA1), KPRS_HELPY  (P56184), 
KPRS_HYPNA  (Q0C5A1), KPRS_LEPIC  (Q72V73), KPRS_LEPIN  (Q8EZN0), 
KPRS_MARMM  (Q0ARN5), KPRS_MARMS  (A6W1C7), KPRS_MYCBO  (P65233), 
KPRS_MYCGE  (P47304), KPRS_MYCLE  (Q9CD45), KPRS_MYCPN  (P75044), 
KPRS_MYCPU  (Q98R83), KPRS_MYCTO  (P9WKE2), KPRS_MYCTU  (P9WKE3), 
KPRS_NEIMA  (P65234), KPRS_NEIMB  (P65235), KPRS_NITEU  (Q82TQ4), 
KPRS_NOSS1  (Q8YN97), KPRS_OCEIH  (Q8EU34), KPRS_PASMU  (Q9CP22), 
KPRS_PHOLL  (Q7N590), KPRS_PORGI  (Q7MT83), KPRS_PROMA  (Q7VBH4), 
KPRS_PROMM  (Q7V6S2), KPRS_PROMP  (Q7V111), KPRS_PSEAE  (Q9HVC5), 
KPRS_PSEPK  (Q88PX6), KPRS_PSESM  (Q888C6), KPRS_RALSO  (Q8Y2E1), 
KPRS_RHILO  (Q98HW3), KPRS_RHIME  (Q92N73), KPRS_RHOBA  (Q7UPM4), 
KPRS_RHOSK  (B9KPJ0), KPRS_SALTI  (P0A1V7), KPRS_SALTY  (P0A1V6), 
KPRS_SHEON  (Q8EAQ9), KPRS_STAAC  (Q5HIH5), KPRS_STAAM  (P65236), 
KPRS_STAAN  (P65237), KPRS_STAAR  (Q6GJH1), KPRS_STAAS  (Q6GBY8), 
KPRS_STAAW  (P65238), KPRS_STAEQ  (Q5HRQ5), KPRS_STAES  (Q8CQU7), 
KPRS_STAHJ  (Q4L3F7), KPRS_STAS1  (Q49V09), KPRS_STRAW  (Q82HE7), 
KPRS_STRCO  (Q9K3U0), KPRS_SYNE7  (Q59988), KPRS_SYNPX  (Q7U7L5), 
KPRS_SYNY3  (Q55848), KPRS_THEAB  (B7IFM5), KPRS_THEMA  (Q9X1W3), 
KPRS_UREPA  (Q9PQV0), KPRS_VIBCH  (Q9KQ22), KPRS_VIBPA  (Q87RN8), 
KPRS_VIBVU  (Q8DFF5), KPRS_VIBVY  (Q7MMZ1), KPRS_WOLSU  (Q7M8J0), 
KPRS_XANAC  (Q8PNU0), KPRS_XANCP  (Q8PC63), KPRS_XYLFA  (Q9PA76), 
KPRS_XYLFT  (Q87A22), KPRS_YERPE  (Q8ZEY2), PRPS1_BOVIN (Q2HJ58), 
PRPS1_HUMAN (P60891), PRPS1_MACFA (Q4R4U3), PRPS1_MOUSE (Q9D7G0), 
PRPS1_PONAB (Q5RFJ7), PRPS1_RAT   (P60892), PRPS2_CHICK (Q5ZI49), 
PRPS2_HUMAN (P11908), PRPS2_MACFA (Q4R4R7), PRPS2_MOUSE (Q9CS42), 
PRPS2_PONAB (Q5R8F8), PRPS2_RAT   (P09330), PRPS2_XENLA (Q7ZXC9), 
PRPS2_XENTR (Q5XGI0), PRPS3_HUMAN (P21108), PRPSA_DICDI (Q54PA9)
» More

UniProtKB/Swiss-Prot
False negative sequences
32 sequences

KPRH_STRCO  (Q9EWS0), KPRS1_ARCFU (O29666), KPRS2_ARCFU (O28853), 
KPRS3_ARATH (Q93Z66), KPRS3_ORYSJ (Q8S2E5), KPRS3_SPIOL (Q9XGA0), 
KPRS4_ARATH (Q680A5), KPRS4_ORYSJ (Q6ZFT5), KPRS4_SPIOL (Q9XGA1), 
KPRS_AERPE  (Q9YAW0), KPRS_AQUAE  (O67556), KPRS_DEIRA  (Q9RUD2), 
KPRS_HALS3  (B0R7B4), KPRS_HALSA  (Q9HN88), KPRS_METAC  (Q8TRK8), 
KPRS_METJA  (Q58761), KPRS_METKA  (Q8TUT6), KPRS_METMA  (Q8PUX3), 
KPRS_METS3  (A5UNK4), KPRS_METTH  (O26877), KPRS_PYRAB  (Q9UY08), 
KPRS_PYRAE  (Q8ZU24), KPRS_PYRFU  (Q8U458), KPRS_PYRHO  (O59586), 
KPRS_SULAC  (Q4J9A6), KPRS_SULSO  (Q97Z86), KPRS_SULTO  (Q973F3), 
KPRS_THEAC  (Q9HLV6), KPRS_THEKO  (O52958), KPRS_THEVO  (Q97CA5), 
PRPSB_DICDI (Q75JN8), PRPSC_DICDI (Q54QU9)
» More

PDB
[Detailed view]
10 PDB

1DKR; 1DKU; 1IBS; 2H06; 2H07; 2H08; 2HCR; 3EFH; 3S5J; 4F8E

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