Due to maintenance work, this service will not be available on Monday December 12th between 07.00 am and 9.00 am CEST.
Entry: PS00114

General information about the entry

Entry name [info] PRPP_SYNTHASE
Accession [info] PS00114
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); OCT-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00105

Name and characterization of the entry

Description [info] Phosphoribosyl pyrophosphate synthase signature.
Pattern [info]
D-[LIM]-H-[SANDT]-x-[QS]-[IMSTAVF]-[QMLPH]-[GA]-[FY]-F-x(2)-P-
[LIVMFCT]-D.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_11 which contains 553'231 sequence entries.


Total number of hits 171 in 171 different sequences
Number of true positive hits 171 in 171 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 32
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 84.24 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] magnesium(?) at position 1
Site [info] magnesium(?) at position 3
Site [info] magnesium(?) at position 15
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
171 sequences

KPR1_CANAX  (P46585    ), KPR1_SCHPO  (P41831    ), KPR1_YEAST  (P32895    ), 
KPR2_SCHPO  (O94413    ), KPR2_YEAST  (P38620    ), KPR3_YEAST  (P38689    ), 
KPR4_YEAST  (P38063    ), KPR5_SCHPO  (P87171    ), KPR5_YEAST  (Q12265    ), 
KPRS1_ARATH (Q42581    ), KPRS1_ENTFA (Q832Z5    ), KPRS1_LACLA (Q9CHB8    ), 
KPRS1_LACPL (Q88Z84    ), KPRS1_LISIN (Q92F68    ), KPRS1_LISMF (Q724L4    ), 
KPRS1_LISMO (Q48793    ), KPRS1_ORYSJ (Q6Z2L5    ), KPRS1_SPIOL (Q9XG98    ), 
KPRS1_STRA3 (Q8E7X8    ), KPRS1_STRA5 (Q8E2H0    ), KPRS1_STRMU (Q8DWM2    ), 
KPRS1_STRP1 (P65243    ), KPRS1_STRP3 (P0DB98    ), KPRS1_STRP6 (Q5XEL0    ), 
KPRS1_STRP8 (P65245    ), KPRS1_STRPN (P65239    ), KPRS1_STRPQ (P0DB99    ), 
KPRS1_STRR6 (P65240    ), KPRS2_ARATH (Q42583    ), KPRS2_ENTFA (Q82ZA5    ), 
KPRS2_LACLA (Q9CEI4    ), KPRS2_LACPL (Q88VA5    ), KPRS2_LISIN (Q92EF1    ), 
KPRS2_LISMF (Q723E1    ), KPRS2_LISMO (Q8Y9L8    ), KPRS2_ORYSJ (Q69XQ6    ), 
KPRS2_SPIOL (Q9XG99    ), KPRS2_STRA3 (Q8E568    ), KPRS2_STRA5 (Q8DZK4    ), 
KPRS2_STRMU (Q8DU94    ), KPRS2_STRP1 (Q99ZR0    ), KPRS2_STRP3 (P0DC00    ), 
KPRS2_STRP6 (Q5XC85    ), KPRS2_STRP8 (Q8P137    ), KPRS2_STRPN (P65241    ), 
KPRS2_STRPQ (P0DC01    ), KPRS2_STRR6 (P65242    ), KPRS5_ARATH (O64888    ), 
KPRS_AGRFC  (Q8UDA9    ), KPRS_BACAN  (Q81VZ0    ), KPRS_BACCL  (P42816    ), 
KPRS_BACCR  (Q81J97    ), KPRS_BACHD  (Q9KGJ5    ), KPRS_BACSU  (P14193    ), 
KPRS_BAUCH  (Q1LTH2    ), KPRS_BIFLO  (Q8G5P2    ), KPRS_BLOFL  (Q7VR76    ), 
KPRS_BORBR  (Q7WNY4    ), KPRS_BORPA  (Q7W181    ), KPRS_BORPE  (Q7VUH1    ), 
KPRS_BRADU  (Q89DJ1    ), KPRS_BRUME  (Q8YIG1    ), KPRS_BRUSU  (Q8FZF0    ), 
KPRS_BUCAI  (P57266    ), KPRS_BUCAP  (Q8K9X2    ), KPRS_BUCBP  (P59512    ), 
KPRS_CALS4  (Q8R753    ), KPRS_CAMJE  (Q9PP15    ), KPRS_CAUCN  (B8GZV1    ), 
KPRS_CAUCR  (Q9AAV6    ), KPRS_CHLTE  (Q8KCQ2    ), KPRS_CHRVO  (Q7NQS9    ), 
KPRS_CLOAB  (Q97E93    ), KPRS_CLOPE  (Q8XHJ4    ), KPRS_CLOTE  (Q899I8    ), 
KPRS_CORAM  (O33924    ), KPRS_COREF  (Q8FQV2    ), KPRS_CORGL  (Q8NRU9    ), 
KPRS_COXBU  (Q83AQ1    ), KPRS_DESPS  (Q6AJL7    ), KPRS_ECO57  (P0A719    ), 
KPRS_ECOL6  (P0A718    ), KPRS_ECOLI  (P0A717    ), KPRS_FUSNN  (Q8RHM2    ), 
KPRS_GLOVI  (Q7NM67    ), KPRS_GRABC  (Q0BPP0    ), KPRS_HAEDU  (Q7VL55    ), 
KPRS_HAEIN  (P44328    ), KPRS_HELHP  (Q7VFY9    ), KPRS_HELPJ  (Q9ZLA1    ), 
KPRS_HELPY  (P56184    ), KPRS_HYPNA  (Q0C5A1    ), KPRS_LEPIC  (Q72V73    ), 
KPRS_LEPIN  (Q8EZN0    ), KPRS_LISIV  (Q83YI7    ), KPRS_LISWE  (Q83TK1    ), 
KPRS_MARMM  (Q0ARN5    ), KPRS_MARMS  (A6W1C7    ), KPRS_MYCBO  (P65233    ), 
KPRS_MYCGE  (P47304    ), KPRS_MYCLE  (Q9CD45    ), KPRS_MYCPN  (P75044    ), 
KPRS_MYCPU  (Q98R83    ), KPRS_MYCTO  (P9WKE2    ), KPRS_MYCTU  (P9WKE3    ), 
KPRS_NEIMA  (P65234    ), KPRS_NEIMB  (P65235    ), KPRS_NITEU  (Q82TQ4    ), 
KPRS_NOSS1  (Q8YN97    ), KPRS_OCEIH  (Q8EU34    ), KPRS_PASMU  (Q9CP22    ), 
KPRS_PHOLL  (Q7N590    ), KPRS_PORGI  (Q7MT83    ), KPRS_PROMA  (Q7VBH4    ), 
KPRS_PROMM  (Q7V6S2    ), KPRS_PROMP  (Q7V111    ), KPRS_PSEAE  (Q9HVC5    ), 
KPRS_PSEPK  (Q88PX6    ), KPRS_PSESM  (Q888C6    ), KPRS_RALSO  (Q8Y2E1    ), 
KPRS_RHILO  (Q98HW3    ), KPRS_RHIME  (Q92N73    ), KPRS_RHOBA  (Q7UPM4    ), 
KPRS_RHOSK  (B9KPJ0    ), KPRS_SALTI  (P0A1V7    ), KPRS_SALTY  (P0A1V6    ), 
KPRS_SHEON  (Q8EAQ9    ), KPRS_STAAC  (Q5HIH5    ), KPRS_STAAM  (P65236    ), 
KPRS_STAAN  (P65237    ), KPRS_STAAR  (Q6GJH1    ), KPRS_STAAS  (Q6GBY8    ), 
KPRS_STAAW  (P65238    ), KPRS_STAEQ  (Q5HRQ5    ), KPRS_STAES  (Q8CQU7    ), 
KPRS_STAHJ  (Q4L3F7    ), KPRS_STAS1  (Q49V09    ), KPRS_STRAW  (Q82HE7    ), 
KPRS_STRCO  (Q9K3U0    ), KPRS_SYNE7  (Q59988    ), KPRS_SYNPX  (Q7U7L5    ), 
KPRS_SYNY3  (Q55848    ), KPRS_THEAB  (B7IFM5    ), KPRS_THEMA  (Q9X1W3    ), 
KPRS_UREPA  (Q9PQV0    ), KPRS_VIBCH  (Q9KQ22    ), KPRS_VIBPA  (Q87RN8    ), 
KPRS_VIBVU  (Q8DFF5    ), KPRS_VIBVY  (Q7MMZ1    ), KPRS_WOLSU  (Q7M8J0    ), 
KPRS_XANAC  (Q8PNU0    ), KPRS_XANCP  (Q8PC63    ), KPRS_XYLFA  (Q9PA76    ), 
KPRS_XYLFT  (Q87A22    ), KPRS_YERPE  (Q8ZEY2    ), PRPS1_BOVIN (Q2HJ58    ), 
PRPS1_HUMAN (P60891    ), PRPS1_MACFA (Q4R4U3    ), PRPS1_MOUSE (Q9D7G0    ), 
PRPS1_PONAB (Q5RFJ7    ), PRPS1_RAT   (P60892    ), PRPS2_CHICK (Q5ZI49    ), 
PRPS2_HUMAN (P11908    ), PRPS2_MACFA (Q4R4R7    ), PRPS2_MOUSE (Q9CS42    ), 
PRPS2_PONAB (Q5R8F8    ), PRPS2_RAT   (P09330    ), PRPS2_XENLA (Q7ZXC9    ), 
PRPS2_XENTR (Q5XGI0    ), PRPS3_HUMAN (P21108    ), PRPSA_DICDI (Q54PA9    )
» more

UniProtKB/Swiss-Prot
False negative sequences
32 sequences

KPRH_STRCO  (Q9EWS0    ), KPRS1_ARCFU (O29666    ), KPRS2_ARCFU (O28853    ), 
KPRS3_ARATH (Q93Z66    ), KPRS3_ORYSJ (Q8S2E5    ), KPRS3_SPIOL (Q9XGA0    ), 
KPRS4_ARATH (Q680A5    ), KPRS4_ORYSJ (Q6ZFT5    ), KPRS4_SPIOL (Q9XGA1    ), 
KPRS_AERPE  (Q9YAW0    ), KPRS_AQUAE  (O67556    ), KPRS_DEIRA  (Q9RUD2    ), 
KPRS_HALS3  (B0R7B4    ), KPRS_HALSA  (Q9HN88    ), KPRS_METAC  (Q8TRK8    ), 
KPRS_METJA  (Q58761    ), KPRS_METKA  (Q8TUT6    ), KPRS_METMA  (Q8PUX3    ), 
KPRS_METS3  (A5UNK4    ), KPRS_METTH  (O26877    ), KPRS_PYRAB  (Q9UY08    ), 
KPRS_PYRAE  (Q8ZU24    ), KPRS_PYRFU  (Q8U458    ), KPRS_PYRHO  (O59586    ), 
KPRS_SULAC  (Q4J9A6    ), KPRS_SULSO  (Q97Z86    ), KPRS_SULTO  (Q973F3    ), 
KPRS_THEAC  (Q9HLV6    ), KPRS_THEKO  (O52958    ), KPRS_THEVO  (Q97CA5    ), 
PRPSB_DICDI (Q75JN8    ), PRPSC_DICDI (Q54QU9    )
» more

PDB
[Detailed view]
15 PDB

1DKR; 1DKU; 1IBS; 2H06; 2H07; 2H08; 2HCR; 3EFH; 3S5J; 4F8E; 4LYG; 4LZN; 4LZO; 4M0P; 4S2U
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission