Entry: PS00114

General information about the entry

Entry name [info] PRPP_SYNTHASE
Accession [info] PS00114
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); MAY-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00105

Name and characterization of the entry

Description [info] Phosphoribosyl pyrophosphate synthase signature.
Pattern [info]
D-[LIM]-H-[SANDT]-x-[QS]-[IMSTAVF]-[QMLPH]-[GA]-[FY]-F-x(2)-P-
[LIVMFCT]-D.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_07 which contains 548'872 sequence entries.


Total number of hits 171 in 171 different sequences
Number of true positive hits 171 in 171 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 32
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 84.24 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] magnesium(?) at position 1
Site [info] magnesium(?) at position 3
Site [info] magnesium(?) at position 15
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
171 sequences

KPR1_CANAX  (P46585), KPR1_SCHPO  (P41831), KPR1_YEAST  (P32895), 
KPR2_SCHPO  (O94413), KPR2_YEAST  (P38620), KPR3_YEAST  (P38689), 
KPR4_YEAST  (P38063), KPR5_SCHPO  (P87171), KPR5_YEAST  (Q12265), 
KPRS1_ARATH (Q42581), KPRS1_ENTFA (Q832Z5), KPRS1_LACLA (Q9CHB8), 
KPRS1_LACPL (Q88Z84), KPRS1_LISIN (Q92F68), KPRS1_LISMF (Q724L4), 
KPRS1_LISMO (Q48793), KPRS1_ORYSJ (Q6Z2L5), KPRS1_SPIOL (Q9XG98), 
KPRS1_STRA3 (Q8E7X8), KPRS1_STRA5 (Q8E2H0), KPRS1_STRMU (Q8DWM2), 
KPRS1_STRP1 (P65243), KPRS1_STRP3 (P0DB98), KPRS1_STRP6 (Q5XEL0), 
KPRS1_STRP8 (P65245), KPRS1_STRPN (P65239), KPRS1_STRPQ (P0DB99), 
KPRS1_STRR6 (P65240), KPRS2_ARATH (Q42583), KPRS2_ENTFA (Q82ZA5), 
KPRS2_LACLA (Q9CEI4), KPRS2_LACPL (Q88VA5), KPRS2_LISIN (Q92EF1), 
KPRS2_LISMF (Q723E1), KPRS2_LISMO (Q8Y9L8), KPRS2_ORYSJ (Q69XQ6), 
KPRS2_SPIOL (Q9XG99), KPRS2_STRA3 (Q8E568), KPRS2_STRA5 (Q8DZK4), 
KPRS2_STRMU (Q8DU94), KPRS2_STRP1 (Q99ZR0), KPRS2_STRP3 (P0DC00), 
KPRS2_STRP6 (Q5XC85), KPRS2_STRP8 (Q8P137), KPRS2_STRPN (P65241), 
KPRS2_STRPQ (P0DC01), KPRS2_STRR6 (P65242), KPRS5_ARATH (O64888), 
KPRS_AGRFC  (Q8UDA9), KPRS_BACAN  (Q81VZ0), KPRS_BACCL  (P42816), 
KPRS_BACCR  (Q81J97), KPRS_BACHD  (Q9KGJ5), KPRS_BACSU  (P14193), 
KPRS_BAUCH  (Q1LTH2), KPRS_BIFLO  (Q8G5P2), KPRS_BLOFL  (Q7VR76), 
KPRS_BORBR  (Q7WNY4), KPRS_BORPA  (Q7W181), KPRS_BORPE  (Q7VUH1), 
KPRS_BRADU  (Q89DJ1), KPRS_BRUME  (Q8YIG1), KPRS_BRUSU  (Q8FZF0), 
KPRS_BUCAI  (P57266), KPRS_BUCAP  (Q8K9X2), KPRS_BUCBP  (P59512), 
KPRS_CALS4  (Q8R753), KPRS_CAMJE  (Q9PP15), KPRS_CAUCN  (B8GZV1), 
KPRS_CAUCR  (Q9AAV6), KPRS_CHLTE  (Q8KCQ2), KPRS_CHRVO  (Q7NQS9), 
KPRS_CLOAB  (Q97E93), KPRS_CLOPE  (Q8XHJ4), KPRS_CLOTE  (Q899I8), 
KPRS_CORAM  (O33924), KPRS_COREF  (Q8FQV2), KPRS_CORGL  (Q8NRU9), 
KPRS_COXBU  (Q83AQ1), KPRS_DESPS  (Q6AJL7), KPRS_ECO57  (P0A719), 
KPRS_ECOL6  (P0A718), KPRS_ECOLI  (P0A717), KPRS_FUSNN  (Q8RHM2), 
KPRS_GLOVI  (Q7NM67), KPRS_GRABC  (Q0BPP0), KPRS_HAEDU  (Q7VL55), 
KPRS_HAEIN  (P44328), KPRS_HELHP  (Q7VFY9), KPRS_HELPJ  (Q9ZLA1), 
KPRS_HELPY  (P56184), KPRS_HYPNA  (Q0C5A1), KPRS_LEPIC  (Q72V73), 
KPRS_LEPIN  (Q8EZN0), KPRS_LISIV  (Q83YI7), KPRS_LISWE  (Q83TK1), 
KPRS_MARMM  (Q0ARN5), KPRS_MARMS  (A6W1C7), KPRS_MYCBO  (P65233), 
KPRS_MYCGE  (P47304), KPRS_MYCLE  (Q9CD45), KPRS_MYCPN  (P75044), 
KPRS_MYCPU  (Q98R83), KPRS_MYCTO  (P9WKE2), KPRS_MYCTU  (P9WKE3), 
KPRS_NEIMA  (P65234), KPRS_NEIMB  (P65235), KPRS_NITEU  (Q82TQ4), 
KPRS_NOSS1  (Q8YN97), KPRS_OCEIH  (Q8EU34), KPRS_PASMU  (Q9CP22), 
KPRS_PHOLL  (Q7N590), KPRS_PORGI  (Q7MT83), KPRS_PROMA  (Q7VBH4), 
KPRS_PROMM  (Q7V6S2), KPRS_PROMP  (Q7V111), KPRS_PSEAE  (Q9HVC5), 
KPRS_PSEPK  (Q88PX6), KPRS_PSESM  (Q888C6), KPRS_RALSO  (Q8Y2E1), 
KPRS_RHILO  (Q98HW3), KPRS_RHIME  (Q92N73), KPRS_RHOBA  (Q7UPM4), 
KPRS_RHOSK  (B9KPJ0), KPRS_SALTI  (P0A1V7), KPRS_SALTY  (P0A1V6), 
KPRS_SHEON  (Q8EAQ9), KPRS_STAAC  (Q5HIH5), KPRS_STAAM  (P65236), 
KPRS_STAAN  (P65237), KPRS_STAAR  (Q6GJH1), KPRS_STAAS  (Q6GBY8), 
KPRS_STAAW  (P65238), KPRS_STAEQ  (Q5HRQ5), KPRS_STAES  (Q8CQU7), 
KPRS_STAHJ  (Q4L3F7), KPRS_STAS1  (Q49V09), KPRS_STRAW  (Q82HE7), 
KPRS_STRCO  (Q9K3U0), KPRS_SYNE7  (Q59988), KPRS_SYNPX  (Q7U7L5), 
KPRS_SYNY3  (Q55848), KPRS_THEAB  (B7IFM5), KPRS_THEMA  (Q9X1W3), 
KPRS_UREPA  (Q9PQV0), KPRS_VIBCH  (Q9KQ22), KPRS_VIBPA  (Q87RN8), 
KPRS_VIBVU  (Q8DFF5), KPRS_VIBVY  (Q7MMZ1), KPRS_WOLSU  (Q7M8J0), 
KPRS_XANAC  (Q8PNU0), KPRS_XANCP  (Q8PC63), KPRS_XYLFA  (Q9PA76), 
KPRS_XYLFT  (Q87A22), KPRS_YERPE  (Q8ZEY2), PRPS1_BOVIN (Q2HJ58), 
PRPS1_HUMAN (P60891), PRPS1_MACFA (Q4R4U3), PRPS1_MOUSE (Q9D7G0), 
PRPS1_PONAB (Q5RFJ7), PRPS1_RAT   (P60892), PRPS2_CHICK (Q5ZI49), 
PRPS2_HUMAN (P11908), PRPS2_MACFA (Q4R4R7), PRPS2_MOUSE (Q9CS42), 
PRPS2_PONAB (Q5R8F8), PRPS2_RAT   (P09330), PRPS2_XENLA (Q7ZXC9), 
PRPS2_XENTR (Q5XGI0), PRPS3_HUMAN (P21108), PRPSA_DICDI (Q54PA9)
» More

UniProtKB/Swiss-Prot
False negative sequences
32 sequences

KPRH_STRCO  (Q9EWS0), KPRS1_ARCFU (O29666), KPRS2_ARCFU (O28853), 
KPRS3_ARATH (Q93Z66), KPRS3_ORYSJ (Q8S2E5), KPRS3_SPIOL (Q9XGA0), 
KPRS4_ARATH (Q680A5), KPRS4_ORYSJ (Q6ZFT5), KPRS4_SPIOL (Q9XGA1), 
KPRS_AERPE  (Q9YAW0), KPRS_AQUAE  (O67556), KPRS_DEIRA  (Q9RUD2), 
KPRS_HALS3  (B0R7B4), KPRS_HALSA  (Q9HN88), KPRS_METAC  (Q8TRK8), 
KPRS_METJA  (Q58761), KPRS_METKA  (Q8TUT6), KPRS_METMA  (Q8PUX3), 
KPRS_METS3  (A5UNK4), KPRS_METTH  (O26877), KPRS_PYRAB  (Q9UY08), 
KPRS_PYRAE  (Q8ZU24), KPRS_PYRFU  (Q8U458), KPRS_PYRHO  (O59586), 
KPRS_SULAC  (Q4J9A6), KPRS_SULSO  (Q97Z86), KPRS_SULTO  (Q973F3), 
KPRS_THEAC  (Q9HLV6), KPRS_THEKO  (O52958), KPRS_THEVO  (Q97CA5), 
PRPSB_DICDI (Q75JN8), PRPSC_DICDI (Q54QU9)
» More

PDB
[Detailed view]
14 PDB

1DKR; 1DKU; 1IBS; 2H06; 2H07; 2H08; 2HCR; 3EFH; 3S5J; 4F8E; 4LYG; 4LZN; 4LZO; 4M0P
» More

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