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PROSITE entry PS00300


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General information about the entry

Entry name [info] SRP54
Accession [info] PS00300
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00272

Name and characterization of the entry

Description [info] SRP54-type proteins GTP-binding domain signature.
Pattern [info]
P-[LIVM]-x-[FYL]-[LIVMAT]-[GS]-{Q}-[GS]-[EQ]-x-{K}-x(2)-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 140 in 140 different sequences
Number of true positive hits 118 in 118 different sequences
Number of 'unknown' hits 0
Number of false positive hits 22 in 22 different sequences
Number of false negative sequences 45
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 84.29 %
Recall (true positives / (true positives + false negatives)) 72.39 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
118 sequences

CFTSY_ARATH (O80842), FTSY_AGRFC  (A9CHH2), FTSY_AQUAE  (O67066), 
FTSY_BACSU  (P51835), FTSY_BIFLO  (Q8G736), FTSY_BUCAI  (P57137), 
FTSY_BUCAP  (Q8KA77), FTSY_BUCBP  (Q89B28), FTSY_DEIRA  (Q9RS67), 
FTSY_ECOLI  (P10121), FTSY_HAEIN  (P44870), FTSY_HALVD  (D4GYW6), 
FTSY_HELPJ  (Q9ZL80), FTSY_HELPY  (O25458), FTSY_METJA  (Q57739), 
FTSY_MYCBO  (P66843), FTSY_MYCGE  (P47539), FTSY_MYCLE  (O33010), 
FTSY_MYCPN  (P75362), FTSY_MYCTO  (P9WGD8), FTSY_MYCTU  (P9WGD9), 
FTSY_NEIGO  (P14929), FTSY_NEIMA  (P57010), FTSY_NEIMB  (P57011), 
FTSY_NEIMC  (O30391), FTSY_NITV2  (Q726P7), FTSY_RICBR  (Q1RKK5), 
FTSY_RICCN  (Q92GB8), FTSY_RICFE  (Q4UK46), FTSY_RICPR  (O05948), 
FTSY_RICTY  (Q68VX4), FTSY_STRMU  (Q8CWX8), FTSY_SULAC  (P27414), 
FTSY_SYNY3  (P73930), FTSY_THEAQ  (P83749), SR541_ARATH (P37106), 
SR541_HORVU (P49968), SR541_SOLLC (P49971), SR542_ARATH (P49966), 
SR542_HORVU (P49969), SR542_SOLLC (P49972), SR543_ARATH (P49967), 
SR543_HORVU (P49970), SR54C_ARATH (P37107), SRP54_AQUAE (O67615), 
SRP54_ARCFU (O29633), SRP54_ASPNG (Q00179), SRP54_BACSU (P37105), 
SRP54_BOVIN (Q2T9U1), SRP54_BUCAI (P57473), SRP54_BUCAP (Q8K9F7), 
SRP54_BUCBP (Q89AE4), SRP54_CANAX (O42816), SRP54_CANLF (P61010), 
SRP54_DANRE (Q7ZVN5), SRP54_DICDI (Q75K18), SRP54_ECO57 (P0AGD9), 
SRP54_ECOL6 (P0AGD8), SRP54_ECOLI (P0AGD7), SRP54_ENTH1 (O15821), 
SRP54_GEOCY (Q8MZJ6), SRP54_HAEIN (P44518), SRP54_HELPJ (Q9ZK62), 
SRP54_HELPY (P56005), SRP54_HUMAN (P61011), SRP54_MACFA (Q4R965), 
SRP54_META3 (A6UWG4), SRP54_METAC (Q8THD0), SRP54_METBF (Q46E01), 
SRP54_METJA (Q57565), SRP54_METKA (Q8TUY9), SRP54_METM5 (A4FVX4), 
SRP54_METM6 (A9A9B0), SRP54_METM7 (A6VHE0), SRP54_METMA (Q8PXF3), 
SRP54_METMP (Q6LX03), SRP54_METS3 (A5UMY7), SRP54_METS5 (A4YHL0), 
SRP54_METST (Q2NE47), SRP54_METTH (O27376), SRP54_METVS (A6UQJ8), 
SRP54_MOUSE (P14576), SRP54_MYCBO (P66845), SRP54_MYCGE (P47294), 
SRP54_MYCMY (Q01442), SRP54_MYCPN (P75054), SRP54_MYCTO (P9WGD6), 
SRP54_MYCTU (P9WGD7), SRP54_PONAB (Q5R4R6), SRP54_PYRAB (Q9V1E8), 
SRP54_PYRFU (Q8U070), SRP54_PYRHO (O59307), SRP54_RAT   (Q6AYB5), 
SRP54_RICBR (Q1RHD6), SRP54_RICCN (Q92J55), SRP54_RICFE (Q4UKH4), 
SRP54_RICPR (Q9ZDZ0), SRP54_RICTY (Q68XJ4), SRP54_SCHPO (P21565), 
SRP54_STRMU (Q54431), SRP54_SYNE7 (Q55311), SRP54_SYNY3 (P74214), 
SRP54_THEAC (Q9HKT0), SRP54_THEAQ (O07347), SRP54_THEGJ (C5A233), 
SRP54_THEKO (Q5JJC8), SRP54_THEON (B6YSS1), SRP54_THEVO (Q979Y8), 
SRP54_YARLI (Q99150), SRP54_YEAST (P20424), SRPRA_BOVIN (Q3MHE8), 
SRPRA_CANLF (P06625), SRPRA_DICDI (Q54ZR7), SRPRA_DROME (Q9U5L1), 
SRPRA_HUMAN (P08240), SRPRA_MOUSE (Q9DBG7), SRPR_SCHPO  (O43032), 
SRPR_YEAST  (P32916)
» more

UniProtKB/Swiss-Prot
False negative sequences
45 sequences

FLHF_AQUAE  (O67266), FLHF_BACSU  (Q01960), FLHF_BORBU  (Q44758), 
FLHF_CAMJE  (O52908), FLHF_HELPJ  (Q9ZM34), FLHF_HELPY  (O25679), 
FLHF_PSEAE  (Q9I3P8), FLHF_PSEPU  (O52256), FLHF_TREPA  (Q56339), 
FTSY_CHLPN  (Q9Z6T7), FTSY_HELM1  (D3UJA7), FTSY_METAC  (Q8TIN7), 
FTSY_METH1  (O32861), FTSY_MYCMS  (Q6MTB9), FTSY_THEAC  (Q9HJ93), 
SRP54_ACIAM (P70722), SRP54_AERPE (Q9YB62), SRP54_HALLT (B9LT33), 
SRP54_HALMA (Q5UY20), SRP54_HALS3 (B0R7X3), SRP54_HALSA (Q9HMN5), 
SRP54_HALVD (Q977V2), SRP54_HALWD (Q18EV2), SRP54_HYPBU (A2BNB5), 
SRP54_METAR (Q0W2G1), SRP54_METBU (Q12ZG8), SRP54_METLZ (A2STI3), 
SRP54_METTP (A0B638), SRP54_MYCLE (O33013), SRP54_NATPD (Q3IUP1), 
SRP54_PYRAE (Q8ZT95), SRP54_PYRAR (A4WLQ3), SRP54_PYRCJ (A3MWX6), 
SRP54_PYRIL (A1RS43), SRP54_PYRNV (B1Y9L4), SRP54_SACS2 (Q97ZE7), 
SRP54_STAMF (A3DML3), SRP54_SULAC (O07853), SRP54_SULIA (C3N5B0), 
SRP54_SULIK (C4KGX6), SRP54_SULIL (C3MPN4), SRP54_SULIM (C3MYM8), 
SRP54_SULIN (C3NHT9), SRP54_SULIY (C3NDW4), SRP54_SULTO (Q971S9)
» more

UniProtKB/Swiss-Prot
False positive sequences
22 sequences

CRN1_PHYIN  (Q8H6Z6), CSPG2_MOUSE (Q62059), CSPG2_RAT   (Q9ERB4), 
CYAH_PSEI1  (E3JD18), DHKM_DICDI  (Q54SK5), EIF3F_CRYNB (P0CO85), 
EIF3F_CRYNJ (P0CO84), INLPA_MYCTU (Q10896), MAMH_MAGGM  (Q6NE63), 
METR_HAEIN  (P45349), NCTSP_BPN4  (A0MZE7), NTPP_ROSDO  (Q16CZ1), 
PURA_THEMA  (Q9X0I1), RDRP_NMV(P15095), SECD_METKA  (Q8TWM4), 
SECD_PYRFU  (Q8U4B4), SEN54_MOUSE (Q8C2A2), SYL1_METS5  (A4YE96), 
SYM_ALBFT   (Q21TB9), SYM_HYPNA   (Q0C161), SYP_PSYIN   (A1SZR1), 
ZYG1_CAEBR  (Q621J7)
» more

PDB
[Detailed view]
74 PDB

1FFH; 1FTS; 1JPJ; 1JPN; 1LS1; 1NG1; 1O87; 1OKK; 1RJ9; 1RY1; 2C03; 2C04; 2CNW; 2FFH; 2IY3; 2IYL; 2J28; 2J37; 2J45; 2J46; 2J7P; 2NG1; 2OG2; 2Q9A; 2Q9B; 2Q9C; 2QY9; 2V3C; 2XKV; 2XXA; 2YHS; 3B9Q; 3DM5; 3NDB; 3NG1; 3ZN8; 4C7O; 4UE5; 5GAD; 5GAF; 5GAG; 5GAH; 5L3Q; 5L3R; 5L3S; 5L3W; 5NCO; 5NIY; 6CQP; 6CS8; 6CVD; 6DLX; 6FQD; 6FRK; 6N5I; 6N5J; 6N6N; 6N9B; 6NC1; 6NC4; 6R6G; 6Y2Z; 6Y30; 6Y31; 6Y32; 7NFX; 7O5B; 7O9F; 7O9G; 7O9H; 7O9I; 7OBQ; 7OBR; 7QWQ
» more