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PROSITE documentation PDOC00056

Ribosomal protein S18 signature





Description

Ribosomal protein S18 is one of the proteins from the small ribosomal subunit. subunit. In Escherichia coli, S18 has been involved in aminoacyl-tRNA binding [1]. It appears to be situated at the tRNA A-site of the ribosome. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [2], groups:

  • Eubacterial S18.
  • Algal and plant chloroplast S18.
  • Cyanelle S18.

As a signature pattern, we selected a conserved region in the central section of the protein. This region contains two basic residues which may be involved in RNA-binding.

Last update:

April 2006 / Pattern revised.

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Technical section

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S18, PS00057; Ribosomal protein S18 signature  (PATTERN)


References

1AuthorsMcDougall J. Choli T. Kruft V. Kapp U. Wittmann-Liebold B.
TitleThe complete amino acid sequence of ribosomal protein S18 from the moderate thermophile Bacillus stearothermophilus.
SourceFEBS Lett. 245:253-260(1989).
PubMed ID2647521

2AuthorsOtaka E. Hashimoto T. Mizuta K.
SourceProtein Seq. Data Anal. 5:285-300(1993).



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