We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00056Ribosomal protein S18 signature
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00056
Description
Ribosomal protein S18 is one of the proteins from the small ribosomal subunit. subunit. In Escherichia coli, S18 has been involved in aminoacyl-tRNA binding [1]. It appears to be situated at the tRNA A-site of the ribosome. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [2], groups:
- Eubacterial S18.
- Algal and plant chloroplast S18.
- Cyanelle S18.
As a signature pattern, we selected a conserved region in the central section of the protein. This region contains two basic residues which may be involved in RNA-binding.
Last update:April 2006 / Pattern revised.
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Technical section
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References
| 1 | Authors | McDougall J. Choli T. Kruft V. Kapp U. Wittmann-Liebold B. |
| Title | The complete amino acid sequence of ribosomal protein S18 from the moderate thermophile Bacillus stearothermophilus. | |
| Source | FEBS Lett. 245:253-260(1989). | |
| PubMed ID | 2647521 |
| 2 | Authors | Otaka E. Hashimoto T. Mizuta K. |
| Source | Protein Seq. Data Anal. 5:285-300(1993). |
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