PROSITE documentation PDOC00056Ribosomal protein S18 signature
Description
Ribosomal protein S18 is one of the proteins from the small ribosomal subunit. subunit. In Escherichia coli, S18 has been involved in aminoacyl-tRNA binding [1]. It appears to be situated at the tRNA A-site of the ribosome. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [2], groups:
- Eubacterial S18.
- Algal and plant chloroplast S18.
- Cyanelle S18.
As a signature pattern, we selected a conserved region in the central section of the protein. This region contains two basic residues which may be involved in RNA-binding.
Last update:April 2006 / Pattern revised.
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Technical section
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References
| 1 | Authors | McDougall J. Choli T. Kruft V. Kapp U. Wittmann-Liebold B. |
| Title | The complete amino acid sequence of ribosomal protein S18 from the moderate thermophile Bacillus stearothermophilus. | |
| Source | FEBS Lett. 245:253-260(1989). | |
| PubMed ID | 2647521 |
| 2 | Authors | Otaka E. Hashimoto T. Mizuta K. |
| Source | Protein Seq. Data Anal. 5:285-300(1993). |
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