Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00281Glycophorin A signature
View entry in original PROSITE document format
View entry in raw text format (no links)
PURL: https://purl.expasy.org/prosite/documentation/PDOC00281
Glycophorin A is the major sialoglycoprotein of erythrocyte membrane [1]. Structurally, glycophorin A consists of an N-terminal extracellular domain, heavily glycosylated on serine and threonine residues, followed by a transmembrane region and a C-terminal cytoplasmic domain.
In human there are two closely related forms: glycophorin A which carries the blood group M/N antigen, and glycophorin B which carries the blood group S/s antigen.
The best conserved region of glycophorin A is the transmembrane domain and we have derived a consensus pattern from that region.
Last update:December 1991 / Pattern and text revised.
-------------------------------------------------------------------------------
PROSITE method (with tools and information) covered by this documentation:
| 1 | Authors | Murayama J.-I. Utsumi H. Hamada A. |
| Title | Amino acid sequence of monkey erythrocyte glycophorin MK. Its amino acid sequence has a striking homology with that of human glycophorin A. | |
| Source | Biochim. Biophys. Acta 999:273-280(1989). | |
| PubMed ID | 2605264 |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.