PROSITE documentation PDOC00310Ribosomal protein L11 signature
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00310
Ribosomal protein L11 is one of the proteins from the large ribosomal subunit. In Escherichia coli, L11 is known to bind directly to the 23S rRNA. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2], groups:
- Eubacterial L11.
- Plant chloroplast L11 (nuclear-encoded).
- Read algal chloroplast L11.
- Cyanelle L11.
- Archaebacterial L11.
- Mammalian L12.
- Plants L12.
- Yeast L12 (YL15).
L11 is a protein of 140 to 165 amino-acid residues. As a signature pattern, we have selected a conserved region located in the C-terminal section of these proteins. In Escherichia coli, the C-terminal half of L11 has been shown [3] to be in an extended and loosely folded conformation and is likely to be buried within the ribosomal structure.
Last update:April 2006 / Pattern revised.
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PROSITE method (with tools and information) covered by this documentation:
| 1 | Authors | Pucciarelli M.G. Remacha M. Vilella M.D. Ballesta J.P.G. |
| Title | The 26S rRNA binding ribosomal protein equivalent to bacterial protein L11 is encoded by unspliced duplicated genes in Saccharomyces cerevisiae. | |
| Source | Nucleic Acids Res. 18:4409-4416(1990). | |
| PubMed ID | 2167467 |
| 2 | Authors | Otaka E. Hashimoto T. Mizuta K. Suzuki K. |
| Source | Protein Seq. Data Anal. 5:301-313(1993). |
| 3 | Authors | Choli T. |
| Title | Structural properties of ribosomal protein L11 from Escherichia coli. | |
| Source | Biochem. Int. 19:1323-1338(1989). | |
| PubMed ID | 2483975 |
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