A number of phosphatidyltransferases, which are all involved in phospholipid
biosynthesis and that share the property of catalyzing the displacement of CMP
from a CDP-alcohol by a second alcohol with formation of a phosphodiester bond
and concomitant breaking of a phosphoride anhydride bond share a conserved
sequence region [1,2]. These enzymes are:
Ethanolaminephosphotransferase (EC 220.127.116.11) from yeast (gene EPT1).
Diacylglycerol cholinephosphotransferase (EC 18.104.22.168) from yeast (gene
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