PROSITE documentation PDOC00387
Ribosomal protein L22 signature


Ribosomal protein L22 is one of the proteins from the large ribosomal subunit. In Escherichia coli, L22 is known to bind 23S rRNA. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2,3], groups:

  • Eubacterial L22.
  • Algal and plant chloroplast L22 (in legumes L22 is encoded in the nucleus instead of the chloroplast).
  • Cyanelle L22.
  • Archaebacterial L22.
  • Mammalian L17.
  • Plant L17.
  • Yeast YL17.

As a signature pattern, we selected a conserved region located in the C-terminal section of these proteins.

Last update:

April 2006 / Pattern revised.


Technical section

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_L22, PS00464; Ribosomal protein L22 signature  (PATTERN)


1AuthorsGantt J.S. Baldauf S.L. Calie P.J. Weeden N.F. Palmer J.D.
TitleTransfer of rpl22 to the nucleus greatly preceded its loss from the chloroplast and involved the gain of an intron.
SourceEMBO J. 10:3073-3078(1991).
PubMed ID1915281

2AuthorsMadsen L.H. Kreiberg J.D. Gausing K.
TitleA small gene family in barley encodes ribosomal proteins homologous to yeast YL17 and L22 from archaebacteria, eubacteria, and chloroplasts.
SourceCurr. Genet. 19:417-422(1991).
PubMed ID1913880

3AuthorsOtaka E. Hashimoto T. Mizuta K. Suzuki K.
SourceProtein Seq. Data Anal. 5:301-313(1993).

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