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PROSITE documentation PDOC00457Ribosomal protein S4e signature
Description
A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:
- Mammalian S4 [1]. Two highly similar isoforms of this protein exist : one coded by a gene on chromosome Y, and the other on chromosome X.
- Plant cytoplasmic S4 [2]
- Yeast S7 (YS6).
- Archebacterial S4e.
These proteins have 233 to 264 amino acids. As a signature pattern, we selected a highly conserved stretch of 15 residues in their N-terminal section. Four positions in this region are positively charged residues.
Last update:July 1999 / Pattern and text revised.
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Technical section
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References
| 1 | Authors | Fisher E.M. Beer-Romero P. Brown L.G. Ridley A. McNeil J.A. Lawrence J.B. Willard H.F. Bieber F.R. Page D.C. |
| Title | Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. | |
| Source | Cell 63:1205-1218(1990). | |
| PubMed ID | 2124517 |
| 2 | Authors | Braun H.P. Emmermann M. Mentzel H. Schmitz U.K. |
| Title | Primary structure and expression of a gene encoding the cytosolic ribosomal protein S4 from potato. | |
| Source | Biochim. Biophys. Acta 1218:435-438(1994). | |
| PubMed ID | 8049269 |
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