PROSITE documentation PDOC00545GHMP kinases putative ATP-binding domain
Description
The following kinases contains, in their N-terminal section, a conserved Gly/ Ser-rich region which is probably involved in the binding of ATP [1]. These kinases are listed below.
- Galactokinase (EC 2.7.1.6).
- Homoserine kinase (EC 2.7.1.39).
- Mevalonate kinase (EC 2.7.1.36).
- Phosphomevalonate kinase (EC 2.7.4.2).
We have called this group of kinases 'GHMP' (from the first letter of their substrate).
Last update:December 2001 / Pattern and text revised.
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Reference
| 1 | Authors | Tsay Y.H. Robinson G.W. |
| Title | Cloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinase. | |
| Source | Mol. Cell. Biol. 11:620-631(1991). | |
| PubMed ID | 1846667 |
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