Escherichia coli protease VII (EC 18.104.22.168) (omptin) (gene ompT)  is an
outer-membrane associated protease with a specificity for paired basic
residues. It seems to be an aspartyl protease  inhibited by zinc ions.
Omptin is highly similar to the following proteins:
Salmonella typhimurium outer membrane protease E (gene pgtE) , also
specific for paired basic residues.
Yersinia pestis coagulase/fibrinolysin (plasminogen activator) (gene pla)
. This enzyme is encoded on a plasmid required for the pathogenic
potential of the bacteria. It cleaves and activates plasminogen at the foci
of infection; this allows plasmin to degrade fibrin barriers thus promoting
the invasiveness of the plague bacteria.
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see prosite_license.html.