We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00757Urotensin II signature
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00757
Description
Urotensin II [1,2] is a small peptide originally isolated from the caudal portion of the spinal cord of teleost and elasmobranch fish but which has also been found in the brain of frogs. Urotensin II seems to be involved in smooth muscle stimulation. It is a peptide of 12 to 13 residues that contains a disulfide bridge.
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xxxxxxCxxxCx
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'C': conserved cysteine involved in a disulfide bond. '*': position of the pattern.Last update:
May 2004 / Text revised.
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Technical section
PROSITE method (with tools and information) covered by this documentation:
References
| 1 | Authors | Conlon J.M. O'Harte F. Smith D.D. Tonon M.-C. Vaudry H. |
| Title | Isolation and primary structure of urotensin II from the brain of a tetrapod, the frog Rana ridibunda. | |
| Source | Biochem. Biophys. Res. Commun. 188:578-583(1992). | |
| PubMed ID | 1445302 |
| 2 | Authors | Conlon J.M. O'Harte F. Smith D.D. Balment R.J. Hazon N. |
| Title | Purification and characterization of urotensin II and parvalbumin from an elasmobranch fish, Scyliorhinus canicula (common dogfish). | |
| Source | Neuroendocrinology 55:230-235(1992). | |
| PubMed ID | 1620290 |
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