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PROSITE documentation PDOC00757Urotensin II signature
Description
Urotensin II [1,2] is a small peptide originally isolated from the caudal portion of the spinal cord of teleost and elasmobranch fish but which has also been found in the brain of frogs. Urotensin II seems to be involved in smooth muscle stimulation. It is a peptide of 12 to 13 residues that contains a disulfide bridge.
+---+ | | xxxxxxCxxxCx ******
'C': conserved cysteine involved in a disulfide bond. '*': position of the pattern.Last update:
May 2004 / Text revised.
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Technical section
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References
1 | Authors | Conlon J.M. O'Harte F. Smith D.D. Tonon M.-C. Vaudry H. |
Title | Isolation and primary structure of urotensin II from the brain of a tetrapod, the frog Rana ridibunda. | |
Source | Biochem. Biophys. Res. Commun. 188:578-583(1992). | |
PubMed ID | 1445302 |
2 | Authors | Conlon J.M. O'Harte F. Smith D.D. Balment R.J. Hazon N. |
Title | Purification and characterization of urotensin II and parvalbumin from an elasmobranch fish, Scyliorhinus canicula (common dogfish). | |
Source | Neuroendocrinology 55:230-235(1992). | |
PubMed ID | 1620290 |
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