We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00775Transcription termination factor nusG signature
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00775
Description
The nusG protein [1,2] is a bacterial transcriptional elongation factor that NusG protein [1,2] is a bacterial transcriptional elongation factor that component of the transcription complex and interacts with the termination factor rho and RNA polymerase.
NusG is a protein of 177 to 353 amino-acid residues [3,4] whose C-terminal sequence is well conserved. We developed a signature pattern from the most conserved part of nusG.
Last update:November 1997 / Pattern and text revised.
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Technical section
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References
| 1 | Authors | Li J. Horwitz R. McCracken S. Greenblatt J. |
| Title | NusG, a new Escherichia coli elongation factor involved in transcriptional antitermination by the N protein of phage lambda. | |
| Source | J. Biol. Chem. 267:6012-6019(1992). | |
| PubMed ID | 1532577 |
| 2 | Authors | Li J. Mason S.W. Greenblatt J. |
| Title | Elongation factor NusG interacts with termination factor rho to regulate termination and antitermination of transcription. | |
| Source | Genes Dev. 7:161-172(1993). | |
| PubMed ID | 8422985 |
| 3 | Authors | Heinrich T. Schroder W. Erdmann V.A. Hartmann R.K. |
| Title | Identification of the gene encoding transcription factor NusG of Thermus thermophilus. | |
| Source | J. Bacteriol. 174:7859-7863(1992). | |
| PubMed ID | 1447157 |
| 4 | Authors | Miyake K. Onaka H. Horinouchi S. Beppu T. |
| Title | Organization and nucleotide sequence of the secE-nusG region of Streptomyces griseus. | |
| Source | Biochim. Biophys. Acta 1217:97-100(1994). | |
| PubMed ID | 8286423 |
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